SAPP: functional genome annotation and analysis through a semantic framework using FAIR principles

Jasper J. Koehorst*, Jesse C.J. van Dam, Edoardo Saccenti, Vitor A.P. Martins Dos Santos, Maria Suarez-Diez, Peter J. Schaap

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

11 Citations (Scopus)

Abstract

To unlock the full potential of genome data and to enhance data interoperability and reusability of genome annotations we have developed SAPP, a Semantic Annotation Platform with Provenance. SAPP is designed as an infrastructure supporting FAIR de novo computational genomics but can also be used to process and analyze existing genome annotations. SAPP automatically predicts, tracks and stores structural and functional annotations and associated dataset- and element-wise provenance in a Linked Data format, thereby enabling information mining and retrieval with Semantic Web technologies. This greatly reduces the administrative burden of handling multiple analysis tools and versions thereof and facilitates multi-level large scale comparative analysis.
Original languageEnglish
Pages (from-to)1401-1403
JournalBioinformatics
Volume34
Issue number8
Early online date23 Nov 2017
DOIs
Publication statusPublished - 15 Apr 2018

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