Abstract
MarA and its homologue, RamA, have been implicated in multidrug resistance (MDR). RamA overexpression in Salmonella enterica serovar Typhimurium and Escherichia coli conferred MDR independently of marA. Inactivation of ramA did not affect the antibiotic susceptibilities of wild-type S. enterica serovar Typhimurium or 15 unrelated clinical MDR isolates. Thus, ramA overexpression is not a common MDR mechanism in Salmonella
| Original language | English |
|---|---|
| Pages (from-to) | 2292-2294 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 48 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2004 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- escherichia-coli
- antibiotic-resistance
- virulence
- confers
- mutants
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