Romantic Surfaces

A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces

Jacob Baggerman, Maarten M.J. Smulders, Han Zuilhof*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Abstract

This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end and side-chain functionalization. Side-chain functionalization methods can be further classified as those that are achieved through homopolymerization of custom-synthesized zwitterionic monomers equipped with reactive groups, or those that are achieved via synthesis of random or block copolymers combining different monomers with antifouling functionality and others with reactive groups. Several of the pros and cons of these approaches are outlined and discussed. Finally, some perspective and future directions of research are presented toward long-term stable, generically repelling surfaces that strongly and specifically adhere to a single component in a complex mixture.

Original languageEnglish
Pages (from-to)1072-1084
JournalLangmuir
Volume35
Issue number5
Early online date8 Jan 2019
DOIs
Publication statusPublished - Feb 2019

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antifouling
Polymers
monomers
Monomers
polymers
Homopolymerization
block copolymers
Complex Mixtures
Block copolymers
copolymers
synthesis

Cite this

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title = "Romantic Surfaces: A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces",
abstract = "This Feature Article focuses on recent advances in the bioconjugation of surface-bound zwitterionic polymers for biospecific antifouling surfaces. Various approaches for the functionalization of antifouling zwitterionic polymers are systematically investigated, such as chain-end and side-chain functionalization. Side-chain functionalization methods can be further classified as those that are achieved through homopolymerization of custom-synthesized zwitterionic monomers equipped with reactive groups, or those that are achieved via synthesis of random or block copolymers combining different monomers with antifouling functionality and others with reactive groups. Several of the pros and cons of these approaches are outlined and discussed. Finally, some perspective and future directions of research are presented toward long-term stable, generically repelling surfaces that strongly and specifically adhere to a single component in a complex mixture.",
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Romantic Surfaces : A Systematic Overview of Stable, Biospecific, and Antifouling Zwitterionic Surfaces. / Baggerman, Jacob; Smulders, Maarten M.J.; Zuilhof, Han.

In: Langmuir, Vol. 35, No. 5, 02.2019, p. 1072-1084.

Research output: Contribution to journalArticleAcademicpeer-review

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