Role for migratory wild birds in the global spread of avian influenza H5N8

Samantha J. Lycett, Rogier Bodewes, Anne Pohlmann, Jill Banks, Krisztián Bányai, Maciej F. Boni, Ruth Bouwstra, Lu Lu

Research output: Contribution to journalArticleAcademicpeer-review

138 Citations (Scopus)

Abstract

Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in January 2014, rapidly spread worldwide in 2014-2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the hemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.

Original languageEnglish
Pages (from-to)213-217
JournalScience
Volume354
Issue number6309
DOIs
Publication statusPublished - 14 Oct 2016

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Influenza in Birds
Poultry
Birds
Orthomyxoviridae
Viruses
Republic of Korea
Hemagglutinins
Neuraminidase
Disease Outbreaks
Public Health
Health

Cite this

Lycett, S. J., Bodewes, R., Pohlmann, A., Banks, J., Bányai, K., Boni, M. F., ... Lu, L. (2016). Role for migratory wild birds in the global spread of avian influenza H5N8. Science, 354(6309), 213-217. https://doi.org/10.1126/science.aaf8852
Lycett, Samantha J. ; Bodewes, Rogier ; Pohlmann, Anne ; Banks, Jill ; Bányai, Krisztián ; Boni, Maciej F. ; Bouwstra, Ruth ; Lu, Lu. / Role for migratory wild birds in the global spread of avian influenza H5N8. In: Science. 2016 ; Vol. 354, No. 6309. pp. 213-217.
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title = "Role for migratory wild birds in the global spread of avian influenza H5N8",
abstract = "Avian influenza viruses affect both poultry production and public health. A subtype H5N8 (clade 2.3.4.4) virus, following an outbreak in poultry in South Korea in January 2014, rapidly spread worldwide in 2014-2015. Our analysis of H5N8 viral sequences, epidemiological investigations, waterfowl migration, and poultry trade showed that long-distance migratory birds can play a major role in the global spread of avian influenza viruses. Further, we found that the hemagglutinin of clade 2.3.4.4 virus was remarkably promiscuous, creating reassortants with multiple neuraminidase subtypes. Improving our understanding of the circumpolar circulation of avian influenza viruses in migratory waterfowl will help to provide early warning of threats from avian influenza to poultry, and potentially human, health.",
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Lycett, SJ, Bodewes, R, Pohlmann, A, Banks, J, Bányai, K, Boni, MF, Bouwstra, R & Lu, L 2016, 'Role for migratory wild birds in the global spread of avian influenza H5N8', Science, vol. 354, no. 6309, pp. 213-217. https://doi.org/10.1126/science.aaf8852

Role for migratory wild birds in the global spread of avian influenza H5N8. / Lycett, Samantha J.; Bodewes, Rogier; Pohlmann, Anne; Banks, Jill; Bányai, Krisztián; Boni, Maciej F.; Bouwstra, Ruth; Lu, Lu.

In: Science, Vol. 354, No. 6309, 14.10.2016, p. 213-217.

Research output: Contribution to journalArticleAcademicpeer-review

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Lycett SJ, Bodewes R, Pohlmann A, Banks J, Bányai K, Boni MF et al. Role for migratory wild birds in the global spread of avian influenza H5N8. Science. 2016 Oct 14;354(6309):213-217. https://doi.org/10.1126/science.aaf8852