C. Bortoluzzi, M. Bosse

Research output: Non-textual formSoftwareOther research output


The repository contains the scripts required to identify runs of homozygosity (ROHs) using whole-genome sequencing data. The scripts implement the method developed by Bosse et al. (2012). A region of homozygosity (ROH) is a contiguous genomic stretch of homozygous genotypes characterized by less variation in an individual than is expected based on the genomic average. These genomic regions are inherited from a common ancestor by both parents (identical haplotypes), and therefore indicate a certain level of relatedness. ROHs are here identified using information on heterozygosity calculated in non-overlapping consecutive windows along the genome.
Original languageEnglish
PublisherWageningen University & Research
Media of outputOnline
Publication statusPublished - 2019

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