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Robustness and efficiency of D-optimal experimental designs in a growth problem

  • M.J. Paulo
  • , D. Rasch

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To assess tree growth, for example in diameter, a forester typically measures the trees at regular time points. We call such designs equidistant. In this paper we look at the robustness and efficiency of several experimental designs, using the D-optimality criterion, in a case study of diameter growth in cork oaks. We compare D-optimal designs (unrestricted and replication-free) with equidistant designs. We further compare designs in different experimental regions. Results indicate that the experimental region should be adequate to the problem, and that D-optimal designs are substantially more efficient than equidistant designs, even under parameter mis-specification.
Original languageEnglish
Pages (from-to)527-540
JournalBiometrical Journal
Volume44
Issue number5
DOIs
Publication statusPublished - 2002

Keywords

  • Experimental designs
  • Growth curves
  • Locally D-optimal designs
  • Nonlinear regression
  • Parameter mis-specification

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