RNAi: prokaryotes get in on the act

J. van der Oost; S.J.J. Brouns

doi:10.1016/j.cell.2009.11.018

RNAi: prokaryotes get in on the act

J. van der Oost, S.J.J. Brouns

Research output: Contribution to journal › Editorial › Academic › peer-review

22 Citations (Scopus)

Abstract

The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA

Original language	English
Pages (from-to)	863-865
Journal	Cell
Volume	139
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2009.11.018
Publication status	Published - 2009

Keywords

interference
machinery
defense

Access to Document

10.1016/j.cell.2009.11.018Licence: Publisher

Cite this

@article{de92b43370e248af8d6000fed23d16c9,

title = "RNAi: prokaryotes get in on the act",

abstract = "The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA",

keywords = "interference, machinery, defense",

author = "{van der Oost}, J. and S.J.J. Brouns",

year = "2009",

doi = "10.1016/j.cell.2009.11.018",

language = "English",

volume = "139",

pages = "863--865",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier",

number = "5",

}

TY - JOUR

T1 - RNAi: prokaryotes get in on the act

AU - van der Oost, J.

AU - Brouns, S.J.J.

PY - 2009

Y1 - 2009

N2 - The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA

AB - The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA

KW - interference

KW - machinery

KW - defense

U2 - 10.1016/j.cell.2009.11.018

DO - 10.1016/j.cell.2009.11.018

M3 - Editorial

SN - 0092-8674

VL - 139

SP - 863

EP - 865

JO - Cell

JF - Cell

IS - 5

ER -

RNAi: prokaryotes get in on the act

Abstract

Keywords

Access to Document

Fingerprint

Cite this