RNAi: prokaryotes get in on the act

J. van der Oost, S.J.J. Brouns

Research output: Contribution to journalEditorialAcademicpeer-review

20 Citations (Scopus)


The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA
Original languageEnglish
Pages (from-to)863-865
Issue number5
Publication statusPublished - 2009


  • interference
  • machinery
  • defense

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