RNAi: prokaryotes get in on the act

J. van der Oost, S.J.J. Brouns

Research output: Contribution to journalEditorialAcademicpeer-review

19 Citations (Scopus)

Abstract

The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA
Original languageEnglish
Pages (from-to)863-865
JournalCell
Volume139
Issue number5
DOIs
Publication statusPublished - 2009

Fingerprint

Clustered Regularly Interspaced Short Palindromic Repeats
Archaea
RNA Interference
Guide RNA
Pyrococcus furiosus
RNA
DNA Viruses
DNA
Adaptive Immunity
Viruses
Bacteria
Plasmids

Keywords

  • interference
  • machinery
  • defense

Cite this

van der Oost, J. ; Brouns, S.J.J. / RNAi: prokaryotes get in on the act. In: Cell. 2009 ; Vol. 139, No. 5. pp. 863-865.
@article{de92b43370e248af8d6000fed23d16c9,
title = "RNAi: prokaryotes get in on the act",
abstract = "The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA",
keywords = "interference, machinery, defense",
author = "{van der Oost}, J. and S.J.J. Brouns",
year = "2009",
doi = "10.1016/j.cell.2009.11.018",
language = "English",
volume = "139",
pages = "863--865",
journal = "Cell",
issn = "0092-8674",
publisher = "Elsevier",
number = "5",

}

RNAi: prokaryotes get in on the act. / van der Oost, J.; Brouns, S.J.J.

In: Cell, Vol. 139, No. 5, 2009, p. 863-865.

Research output: Contribution to journalEditorialAcademicpeer-review

TY - JOUR

T1 - RNAi: prokaryotes get in on the act

AU - van der Oost, J.

AU - Brouns, S.J.J.

PY - 2009

Y1 - 2009

N2 - The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA

AB - The small CRISPR-derived RNAs of bacteria and archaea provide adaptive immunity by targeting the DNA of invading viruses and plasmids. Hale et al. (2009) now report on a new variant CRISPR/Cas complex in the archaeon Pyrococcus furiosus that uses guide RNAs to specifically target and cleave RNA not DNA

KW - interference

KW - machinery

KW - defense

U2 - 10.1016/j.cell.2009.11.018

DO - 10.1016/j.cell.2009.11.018

M3 - Editorial

VL - 139

SP - 863

EP - 865

JO - Cell

JF - Cell

SN - 0092-8674

IS - 5

ER -