Replacing animal experiments in developmental toxicity testing of phenols by combining in vitro assays with physiologically based kinetic (PBK) modelling

Marije Strikwold

Replacing animal experiments in developmental toxicity testing of phenols by combining in vitro assays with physiologically based kinetic (PBK) modelling

Marije Strikwold

Research output: Thesis › internal PhD, WU

Original language	English
Qualification	Doctor of Philosophy
Awarding Institution	Wageningen University
Supervisors/Advisors	Rietjens, Ivonne, Promotor Woutersen, Ruud, Promotor Punt, Ans, Co-promotor
Award date	29 Apr 2016
Place of Publication	Wageningen
Publisher	Wageningen University
Print ISBNs	9789462576926
Publication status	Published - 2016

Keywords

animal experiments
animal testing alternatives
toxicity
testing
phenols
in vitro
embryonic stem cells
tissues
cells
dosage
toxicology
animal health

Access to Document

https://edepot.wur.nl/380090

Implementation of (Q)SAR and physiologically-based kinetic (PBK) modeling techniques into a (Q)SAR-PBK approach for predicting dose-response relationships for rat and human and deriving safe exposure
Strikwold, M., Rietjens, I., Woutersen, R. & Punt, A.
1/03/10 → 29/04/16
Project: PhD

Cite this

@phdthesis{b8a63e2e05584b60b5f2a146bd255458,

title = "Replacing animal experiments in developmental toxicity testing of phenols by combining in vitro assays with physiologically based kinetic (PBK) modelling",

keywords = "animal experiments, animal testing alternatives, toxicity, testing, phenols, in vitro, embryonic stem cells, tissues, cells, dosage, toxicology, animal health, dierproeven, alternatieven voor dierproeven, toxiciteit, testen, fenolen, in vitro, embryonale stamcellen, weefsels, cellen, dosering, toxicologie, diergezondheid",

author = "Marije Strikwold",

note = "WU thesis 6337",

year = "2016",

language = "English",

isbn = "9789462576926",

publisher = "Wageningen University",

school = "Wageningen University",

}

TY - THES

T1 - Replacing animal experiments in developmental toxicity testing of phenols by combining in vitro assays with physiologically based kinetic (PBK) modelling

AU - Strikwold, Marije

N1 - WU thesis 6337

PY - 2016

Y1 - 2016

KW - animal experiments

KW - animal testing alternatives

KW - toxicity

KW - testing

KW - phenols

KW - in vitro

KW - embryonic stem cells

KW - tissues

KW - cells

KW - dosage

KW - toxicology

KW - animal health

KW - dierproeven

KW - alternatieven voor dierproeven

KW - toxiciteit

KW - testen

KW - fenolen

KW - in vitro

KW - embryonale stamcellen

KW - weefsels

KW - cellen

KW - dosering

KW - toxicologie

KW - diergezondheid

M3 - internal PhD, WU

SN - 9789462576926

PB - Wageningen University

CY - Wageningen

ER -

Replacing animal experiments in developmental toxicity testing of phenols by combining in vitro assays with physiologically based kinetic (PBK) modelling

Keywords

Access to Document

Projects

Implementation of (Q)SAR and physiologically-based kinetic (PBK) modeling techniques into a (Q)SAR-PBK approach for predicting dose-response relationships for rat and human and deriving safe exposure

Cite this