Reductive Glycine Pathway: A Versatile Route for One-Carbon Biotech

Nico J. Claassens*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review


Hong et al. heterologously expressed the metabolic core of the reductive glycine pathway (rGlyP) as a sink for the anaerobic conversion of glycerol. This recent study concludes several reports in 2020 on the ATP-efficient, one-carbon-assimilating, rGlyP. Its engineering in diverse hosts could help the transformation toward renewable, one-carbon-based bioproduction.

Original languageEnglish
Pages (from-to)327-329
JournalTrends in Biotechnology
Issue number4
Publication statusPublished - Apr 2021

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