Recombinant activation-associated secreted protein

Peter Geldhof; Laurens Zwanenburg; Jimmy Borloo; Ruud Wilbers; Cornelis Hendrik Hokke; Angela Van Diepen

Recombinant activation-associated secreted protein

Peter Geldhof (Inventor), Laurens Zwanenburg (Inventor), Jimmy Borloo (Inventor), Ruud Wilbers (Inventor), Cornelis Hendrik Hokke (Inventor), Angela Van Diepen (Inventor)

Research output: Patent

Abstract

The present invention relates to a recombinant activation-associated secreted protein (ASP) or fragment thereof, said ASP or fragment comprising an N-glycan comprising a core α1,3-fucose and/or a core α1,6-fucose (Fuc). The invention further relates to a pharmaceutical composition comprising such a recombinant ASP or fragment thereof. Additionally, the invention relates to the recombinant ASP or fragment thereof for use as a human or veterinary medicine, in particular as a vaccine, more in particular for use against parasitic nematode infections.

Original language	English
Patent number	WO2024089248
Priority date	27/10/22
Publication status	Published - 2 May 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Cite this

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title = "Recombinant activation-associated secreted protein",

abstract = "The present invention relates to a recombinant activation-associated secreted protein (ASP) or fragment thereof, said ASP or fragment comprising an N-glycan comprising a core α1,3-fucose and/or a core α1,6-fucose (Fuc). The invention further relates to a pharmaceutical composition comprising such a recombinant ASP or fragment thereof. Additionally, the invention relates to the recombinant ASP or fragment thereof for use as a human or veterinary medicine, in particular as a vaccine, more in particular for use against parasitic nematode infections.",

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T1 - Recombinant activation-associated secreted protein

AU - Geldhof, Peter

AU - Zwanenburg, Laurens

AU - Borloo, Jimmy

AU - Wilbers, Ruud

AU - Hokke, Cornelis Hendrik

AU - Van Diepen, Angela

PY - 2024/5/2

Y1 - 2024/5/2

N2 - The present invention relates to a recombinant activation-associated secreted protein (ASP) or fragment thereof, said ASP or fragment comprising an N-glycan comprising a core α1,3-fucose and/or a core α1,6-fucose (Fuc). The invention further relates to a pharmaceutical composition comprising such a recombinant ASP or fragment thereof. Additionally, the invention relates to the recombinant ASP or fragment thereof for use as a human or veterinary medicine, in particular as a vaccine, more in particular for use against parasitic nematode infections.

AB - The present invention relates to a recombinant activation-associated secreted protein (ASP) or fragment thereof, said ASP or fragment comprising an N-glycan comprising a core α1,3-fucose and/or a core α1,6-fucose (Fuc). The invention further relates to a pharmaceutical composition comprising such a recombinant ASP or fragment thereof. Additionally, the invention relates to the recombinant ASP or fragment thereof for use as a human or veterinary medicine, in particular as a vaccine, more in particular for use against parasitic nematode infections.

M3 - Patent

M1 - WO2024089248

ER -

Recombinant activation-associated secreted protein

Abstract

UN SDGs

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