Recognition of Verticillium effector Ave1 by tomato immune receptor Ve1 mediates Verticillium resistance in diverse plant species

Yin Song

Research output: Thesisinternal PhD, WU

Abstract

Plant-pathogenic microbes secrete effector molecules to establish disease on their hosts, whereas plants in turn employ immune receptors to try and intercept such effectors in order to prevent pathogen colonization. Based on structure and subcellular location, immune receptors fall into two major classes; cell surface-localized receptors that comprise receptor kinases (RKs) and receptor-like proteins (RLPs) that monitor the extracellular space, and cytoplasm-localized nucleotide-binding domain leucine-rich repeat receptors (NLRs) that survey the intracellular environment. Race-specific resistance to Verticillium wilt in tomato (Solanum lycopersicum) is governed by the tomato extracellular leucine-rich repeat (eLRR)-containing RLP-type cell surface receptor Ve1 upon recognition of the effector protein Ave1 that is secreted by race 1 strains of the soil-borne vascular wilt Verticillium dahliae. Homologues of V. dahliae Ave1 (VdAve1) are found in plants and in a number of plant pathogenic microbes, and some of these VdAve1 homologues are recognized by tomato Ve1. The research presented in this thesis aims to characterize the role of the tomato cell surface-localized immune receptor Ve1, and its homologues in other diverse plant species, in Verticillium wilt resistance.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Thomma, Bart, Promotor
  • de Wit, Pierre, Promotor
Award date23 Oct 2017
Place of PublicationWageningen
Publisher
Print ISBNs9789463437950
DOIs
Publication statusPublished - 2017

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Keywords

  • disease resistance
  • defence mechanisms
  • immunity
  • plant-microbe interactions
  • plant pathogens
  • verticillium dahliae
  • verticillium
  • tomatoes
  • solanum lycopersicum
  • receptors
  • genes
  • tobacco
  • nicotiana glutinosa
  • potatoes
  • solanum tuberosum
  • solanum torvum
  • humulus lupulus
  • cotton
  • gossypium hirsutum
  • transgenic plants
  • arabidopsis thaliana

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