Receptor kinase module targets PIN-dependent auxin transport during canalization

Jakub Hajný, Tomáš Prát, Nikola Rydza, Lesia Rodriguez, Shutang Tan, Inge Verstraeten, David Domjan, Ewa Mazur, Elwira Smakowska-Luzan, Wouter Smet, Eliana Mor, Jonah Nolf, Bao Jun Yang, Wim Grunewald, Gergely Molnár, Youssef Belkhadir, Bert De Rybel, Jiří Friml*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Abstract

Spontaneously arising channels that transport the phytohormone auxin provide positional cues for self-organizing aspects of plant development such as flexible vasculature regeneration or its patterning during leaf venation. The auxin canalization hypothesis proposes a feedback between auxin signaling and transport as the underlying mechanism, but molecular players await discovery. We identified part of the machinery that routes auxin transport. The auxin-regulated receptor CAMEL (Canalization-related Auxin-regulated Malectin-type RLK) together with CANAR (Canalization-related Receptor-like kinase) interact with and phosphorylate PIN auxin transporters. camel and canar mutants are impaired in PIN1 subcellular trafficking and auxin-mediated PIN polarization, which macroscopically manifests as defects in leaf venation and vasculature regeneration after wounding. The CAMEL-CANAR receptor complex is part of the auxin feedback that coordinates polarization of individual cells during auxin canalization.

Original languageEnglish
Pages (from-to)550-557
Number of pages8
JournalScience (New York, N.Y.)
Volume370
Issue number6516
DOIs
Publication statusPublished - 30 Oct 2020

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