Ready for regulatory use: NAMs and NGRA for chemical safety assurance

Paul L. Carmichael*, Maria T. Baltazar, Sophie Cable, Stella Cochrane, Matthew Dent, Hequn Li, Alistair Middleton, Iris Muller, Georgia Reynolds, Carl Westmoreland, Andrew White

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademic

27 Citations (Scopus)

Abstract

New approach methodologies (NAMs) that do not use experimental animals are, in certain settings, entirely appropriate for assuring the safety of chemical ingredients, although regulatory adoption has been slow. In this opinion article we discuss how scientific advances that utilize NAMs to certify systemic safety are available now and merit broader acceptance within the framework of next generation risk assessments (NGRA).

Original languageEnglish
Pages (from-to)359-366
Number of pages8
JournalAltex
Volume39
Issue number3
DOIs
Publication statusPublished - 20 Jul 2022

Keywords

  • chemical safety
  • new approach methodologies (NAMs)
  • next generation risk assessement (NGRA)
  • non-animal approaches

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