Rate of Foot-and mouth Disease Virus Transmission by Carriers Quantified from Experimental Data

A. Dekker, J.C.M. Vernooij, A. Bouma, J.A. Stegeman

    Research output: Contribution to journalArticleAcademicpeer-review

    53 Citations (Scopus)

    Abstract

    Upon infection with foot-and-mouth disease virus (FMDV) a considerable number of animals become carriers of the virus. These carriers are considered to be a risk for new outbreaks, but the rate at which these animals can transmit the infection has not been quantified. An analysis was carried out using data from previously published experiments in order to quantify the transmission rate parameter ß of FMDV infection from carriers to susceptible animals. The parameter ß was estimated at 0.0256 (likelihood-based confidence interval: 0.008¿0.059) infections per carrier per month. Moreover, analysis of published experimental data indicates that the proportion of FMDV carriers decreases at a rate of 0.115 per month. Both parameters obtained from this study are useful for quantitative risk analyses of the trade of animals from FMDV-infected areas or the lifting of vaccination programs.
    Original languageEnglish
    Pages (from-to)303-309
    JournalRisk Analysis
    Volume28
    Issue number2
    DOIs
    Publication statusPublished - 2008

    Keywords

    • buffalo syncerus-caffer
    • african buffalo
    • cattle
    • infection
    • pigs
    • vaccination
    • persistence
    • state

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