Abstract
Background: Random serial sampling is widely used in population pharmacokinetic studies and may have advantages compared with conventional fixed time-point evaluation of iron fortification.
Objective: Our objective was to validate random serial sampling to judge the efficacy of iron fortification of a low-fat margarine.
Design: We conducted a 32-wk placebo-controlled, double-blind, iron-intervention trial in 18–40-y-old Swiss women (n = 142) with serum ferritin (SF) concentrations
Original language | English |
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Pages (from-to) | 1094-1104 |
Journal | American Journal of Clinical Nutrition |
Volume | 92 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2010 |
Keywords
- population pharmacokinetics
- relative bioavailability
- double-blind
- transferrin receptor
- dual fortification
- whole diet
- deficiency
- absorption
- iodine
- salt