Qualitative Aspects in the Analysis of Pesticide Residues in Fruits and Vegetables Using Fast, Low -Pressure Gas Chromatography-Time-of-Flight Mass Spectrometry

S.J. Lehotay, U. Koesukwiwat, H.J. van der Kamp, J.G.J. Mol, N. Leepipatpiboon

    Research output: Contribution to journalArticleAcademicpeer-review

    35 Citations (Scopus)

    Abstract

    Quantitative method validation is a well-established process to demonstrate trueness and precision of the results with a given method. However, an assessment of qualitative results is also an important need to estimate selectivity and devise criteria for chemical identification when using the method, particularly for mass spectrometric analysis. For multianalyte analysis, automatic instrument software is commonly used to make initial qualitative identifications of the target analytes by comparison of their mass spectra against a database library. Especially at low residue levels in complex matrices, manual checking of results is typically needed to correct the peak assignments and integration errors, which is very time-consuming. Low-pressure gas chromatography-mass spectrometry (LP-GC-MS) has been demonstrated to increase the speed of analysis for GC-amenable residues in various foods and provide more advantages over the traditional GC-MS approach. LP-GC-MS on a time-of-flight (ToF) instrument was used, which provided high sample throughput with
    Original languageEnglish
    Pages (from-to)7544-7556
    JournalJournal of Agricultural and Food Chemistry
    Volume59
    Issue number14
    DOIs
    Publication statusPublished - 2011

    Keywords

    • gc-ms
    • spectral deconvolution
    • identification system
    • multiresidue method
    • quechers
    • confirmation
    • extraction
    • food

    Fingerprint Dive into the research topics of 'Qualitative Aspects in the Analysis of Pesticide Residues in Fruits and Vegetables Using Fast, Low -Pressure Gas Chromatography-Time-of-Flight Mass Spectrometry'. Together they form a unique fingerprint.

  • Cite this