QTL Mapping in the Evolutionary Context

J.C.P. Prins

Research output: Contribution to conferenceAbstractAcademic

Abstract

QTL Mapping in the Evolutionary Context Pjotr Prins Laboratory of Nematology, Wageningen University and the Groningen Bioinformatics Cente, The Netherlands QTL mapping, both with genome-wide association studies (GWAS) and linkage studies in experimental populations, is a proven statistical method for disentangling complex traits. Especially now, with the deluge of data and information generated by, for example, RNA-seq, a well designed QTL experiment promises a chance of gaining enough statistical power to say something about multi-gene regulation and interaction. Here we discuss elucidating host-pathogen protein-protein interactions through linkage studies, where evidence of positive selection pressure acts as a prior to QTL analysis.
Original languageEnglish
Publication statusPublished - 2011
EventZurich Colloquium for Computational Molecular Evolution (2011) -
Duration: 23 Nov 2011 → …

Conference

ConferenceZurich Colloquium for Computational Molecular Evolution (2011)
Period23/11/11 → …

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