Proteomic and mechanistic analysis of Auxin Response Factors in the Arabidopsis embryo

Research output: Thesisinternal PhD, WUAcademic

Abstract

Auxin is a phytohormone that is crucial for many aspects of plant development. The processes in which this hormone has been implicated span from embryo development to flower transition, defense, tropic responses, and many other processes during plant life. A key question in auxin biology is how this molecule is able to elicit such diverse responses. Auxin regulates the transcriptional activation or repression of genes through the AUXIN RESPONSE FACTOR (ARF) family of transcription factors. In my studies I focus in the ARF transcription factors as a likely source of variation in output specificity. We consider three levels at which ARFs differ. First, ARFs differ in their ability to interact with different Aux/IAA (antagonistic family of transcription factors), or to form homo- or heterodimers. Second, ARFs assemble into different protein complexes, transcription factors interact with other transcriptional regulators or other proteins to form transcription complexes. These, when different, may contribute to different functions of ARF complexes. Thirdly, ARFs  bind to and regulate different target genes. My work offers a plausible explanation how specific auxin responses are generated and through which genes the developmental responses to auxin are generated.

LanguageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Weijers, Dolf, Promotor
Award date4 Oct 2013
Place of PublicationS.l.
Publisher
Print ISBNs9789461736734
Publication statusPublished - 2013

Fingerprint

embryo (plant)
proteomics
auxins
transcription factors
Arabidopsis
genes
Homo
transcriptional activation
plant hormones
indole acetic acid
plant development
tropics
embryogenesis
proteins
transcription (genetics)
hormones
flowers
Biological Sciences

Keywords

  • arabidopsis
  • auxins
  • plant growth regulators
  • responses
  • proteomics
  • gene expression
  • embryonic development
  • embryogenesis

Cite this

@phdthesis{c753e1fbade44f5188f6138407242bdc,
title = "Proteomic and mechanistic analysis of Auxin Response Factors in the Arabidopsis embryo",
abstract = "Auxin is a phytohormone that is crucial for many aspects of plant development. The processes in which this hormone has been implicated span from embryo development to flower transition, defense, tropic responses, and many other processes during plant life. A key question in auxin biology is how this molecule is able to elicit such diverse responses. Auxin regulates the transcriptional activation or repression of genes through the AUXIN RESPONSE FACTOR (ARF) family of transcription factors. In my studies I focus in the ARF transcription factors as a likely source of variation in output specificity. We consider three levels at which ARFs differ. First, ARFs differ in their ability to interact with different Aux/IAA (antagonistic family of transcription factors), or to form homo- or heterodimers. Second, ARFs assemble into different protein complexes, transcription factors interact with other transcriptional regulators or other proteins to form transcription complexes. These, when different, may contribute to different functions of ARF complexes. Thirdly, ARFs  bind to and regulate different target genes. My work offers a plausible explanation how specific auxin responses are generated and through which genes the developmental responses to auxin are generated.",
keywords = "arabidopsis, auxinen, plantengroeiregulatoren, reacties, eiwitexpressieanalyse, genexpressie, embryonale ontwikkeling, embryogenese, arabidopsis, auxins, plant growth regulators, responses, proteomics, gene expression, embryonic development, embryogenesis",
author = "{Llavata Peris}, C.I.",
note = "WU thesis 5556",
year = "2013",
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publisher = "s.n.",
school = "Wageningen University",

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Proteomic and mechanistic analysis of Auxin Response Factors in the Arabidopsis embryo. / Llavata Peris, C.I.

S.l. : s.n., 2013. 143 p.

Research output: Thesisinternal PhD, WUAcademic

TY - THES

T1 - Proteomic and mechanistic analysis of Auxin Response Factors in the Arabidopsis embryo

AU - Llavata Peris, C.I.

N1 - WU thesis 5556

PY - 2013

Y1 - 2013

N2 - Auxin is a phytohormone that is crucial for many aspects of plant development. The processes in which this hormone has been implicated span from embryo development to flower transition, defense, tropic responses, and many other processes during plant life. A key question in auxin biology is how this molecule is able to elicit such diverse responses. Auxin regulates the transcriptional activation or repression of genes through the AUXIN RESPONSE FACTOR (ARF) family of transcription factors. In my studies I focus in the ARF transcription factors as a likely source of variation in output specificity. We consider three levels at which ARFs differ. First, ARFs differ in their ability to interact with different Aux/IAA (antagonistic family of transcription factors), or to form homo- or heterodimers. Second, ARFs assemble into different protein complexes, transcription factors interact with other transcriptional regulators or other proteins to form transcription complexes. These, when different, may contribute to different functions of ARF complexes. Thirdly, ARFs  bind to and regulate different target genes. My work offers a plausible explanation how specific auxin responses are generated and through which genes the developmental responses to auxin are generated.

AB - Auxin is a phytohormone that is crucial for many aspects of plant development. The processes in which this hormone has been implicated span from embryo development to flower transition, defense, tropic responses, and many other processes during plant life. A key question in auxin biology is how this molecule is able to elicit such diverse responses. Auxin regulates the transcriptional activation or repression of genes through the AUXIN RESPONSE FACTOR (ARF) family of transcription factors. In my studies I focus in the ARF transcription factors as a likely source of variation in output specificity. We consider three levels at which ARFs differ. First, ARFs differ in their ability to interact with different Aux/IAA (antagonistic family of transcription factors), or to form homo- or heterodimers. Second, ARFs assemble into different protein complexes, transcription factors interact with other transcriptional regulators or other proteins to form transcription complexes. These, when different, may contribute to different functions of ARF complexes. Thirdly, ARFs  bind to and regulate different target genes. My work offers a plausible explanation how specific auxin responses are generated and through which genes the developmental responses to auxin are generated.

KW - arabidopsis

KW - auxinen

KW - plantengroeiregulatoren

KW - reacties

KW - eiwitexpressieanalyse

KW - genexpressie

KW - embryonale ontwikkeling

KW - embryogenese

KW - arabidopsis

KW - auxins

KW - plant growth regulators

KW - responses

KW - proteomics

KW - gene expression

KW - embryonic development

KW - embryogenesis

M3 - internal PhD, WU

SN - 9789461736734

PB - s.n.

CY - S.l.

ER -