Production of neosolaniol by Fusarium tumidum

Claudio Altomare; Alberto Ritieni; Giancarlo Perrone; Vincenzo Fogliano; Luisa Mannina; Antonio Logrieco

doi:10.1007/BF01103102

Production of neosolaniol by Fusarium tumidum

Claudio Altomare^*, Alberto Ritieni, Giancarlo Perrone, Vincenzo Fogliano, Luisa Mannina, Antonio Logrieco

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

Extracts from autoclaved maize culture of Fusarium tumidum strain R-5823 were toxic towards Artemia salina. Bioassay-guided fractionation of the organic extract led to the isolation of the toxic compound that was identified as the trichothecene toxin neosolaniol (NEOS) by¹H,¹³C nuclear magnetic resonance spectroscopy and low-resolution electronic impact mass spectrometry. The amount of NEOS produced by the strain R-5823 was 300 mg/kg maize culture. NEOS was also detected by HPLC in cultures of four out of seven additional strains of F. tumidum and Gibberella tumida with different origin, in amounts ranging from 1 to 311 mg/kg. This is the first report on the production of a trichothecene toxin by F. tumidum.

Original language	English
Pages (from-to)	179-184
Number of pages	6
Journal	Mycopathologia
Volume	130
Issue number	3
DOIs	https://doi.org/10.1007/BF01103102
Publication status	Published - Jun 1995
Externally published	Yes

Keywords

Fusarium tumidum
Mycotoxins
Neosolaniol
Trichothecenes

Access to Document

10.1007/BF01103102

Cite this

@article{c173a05e7ccb44b2a698d7bde148363e,

title = "Production of neosolaniol by Fusarium tumidum",

abstract = "Extracts from autoclaved maize culture of Fusarium tumidum strain R-5823 were toxic towards Artemia salina. Bioassay-guided fractionation of the organic extract led to the isolation of the toxic compound that was identified as the trichothecene toxin neosolaniol (NEOS) by1H,13C nuclear magnetic resonance spectroscopy and low-resolution electronic impact mass spectrometry. The amount of NEOS produced by the strain R-5823 was 300 mg/kg maize culture. NEOS was also detected by HPLC in cultures of four out of seven additional strains of F. tumidum and Gibberella tumida with different origin, in amounts ranging from 1 to 311 mg/kg. This is the first report on the production of a trichothecene toxin by F. tumidum.",

keywords = "Fusarium tumidum, Mycotoxins, Neosolaniol, Trichothecenes",

author = "Claudio Altomare and Alberto Ritieni and Giancarlo Perrone and Vincenzo Fogliano and Luisa Mannina and Antonio Logrieco",

year = "1995",

month = jun,

doi = "10.1007/BF01103102",

language = "English",

volume = "130",

pages = "179--184",

journal = "Mycopathologia",

issn = "0301-486X",

publisher = "Springer",

number = "3",

}

TY - JOUR

T1 - Production of neosolaniol by Fusarium tumidum

AU - Altomare, Claudio

AU - Ritieni, Alberto

AU - Perrone, Giancarlo

AU - Fogliano, Vincenzo

AU - Mannina, Luisa

AU - Logrieco, Antonio

PY - 1995/6

Y1 - 1995/6

N2 - Extracts from autoclaved maize culture of Fusarium tumidum strain R-5823 were toxic towards Artemia salina. Bioassay-guided fractionation of the organic extract led to the isolation of the toxic compound that was identified as the trichothecene toxin neosolaniol (NEOS) by1H,13C nuclear magnetic resonance spectroscopy and low-resolution electronic impact mass spectrometry. The amount of NEOS produced by the strain R-5823 was 300 mg/kg maize culture. NEOS was also detected by HPLC in cultures of four out of seven additional strains of F. tumidum and Gibberella tumida with different origin, in amounts ranging from 1 to 311 mg/kg. This is the first report on the production of a trichothecene toxin by F. tumidum.

AB - Extracts from autoclaved maize culture of Fusarium tumidum strain R-5823 were toxic towards Artemia salina. Bioassay-guided fractionation of the organic extract led to the isolation of the toxic compound that was identified as the trichothecene toxin neosolaniol (NEOS) by1H,13C nuclear magnetic resonance spectroscopy and low-resolution electronic impact mass spectrometry. The amount of NEOS produced by the strain R-5823 was 300 mg/kg maize culture. NEOS was also detected by HPLC in cultures of four out of seven additional strains of F. tumidum and Gibberella tumida with different origin, in amounts ranging from 1 to 311 mg/kg. This is the first report on the production of a trichothecene toxin by F. tumidum.

KW - Fusarium tumidum

KW - Mycotoxins

KW - Neosolaniol

KW - Trichothecenes

U2 - 10.1007/BF01103102

DO - 10.1007/BF01103102

M3 - Article

C2 - 7566071

AN - SCOPUS:0029310562

SN - 0301-486X

VL - 130

SP - 179

EP - 184

JO - Mycopathologia

JF - Mycopathologia

IS - 3

ER -

Production of neosolaniol by Fusarium tumidum

Abstract

Keywords

Access to Document

Fingerprint

Cite this