Production of fatty acid estolides

C.G. Boeriu (Inventor), Anamaria Todea (Inventor), I.W.C.E. Arends (Inventor), L.G. Otten (Inventor)

Research output: PatentOther research output


It has been found that esterification of a hydroxy-fatty acid by a lipase can be coupled with oleate hydratase (OHase) generation of that hydroxy-FA from an unsaturated FA with a cis C9-C10 double bond, e.g. oleic acid, in a single aqueous buffered reaction medium at low temperature,e.g. 30° C. A simple one-pot enzymatic method to produce fatty acid estolides from one or more triglycerides, e.g. starting from a natural plant oil, is thereby enabled in which the same lipase catalyses both the initial hydrolysis of triglyceride and the final esterification step.
Original languageEnglish
Patent numberWO2016151115
Priority date26/03/15
Publication statusPublished - 29 Sep 2016


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