Process for the preparation of a d-alfa-amino acid from the corresponding alfa-keto acid.

A.J.J. van den Tweel (Inventor), L.H.P. Ogg (Inventor), J.A.M. de Bont (Inventor)

Research output: PatentOther research output

Abstract

The invention relates to a process for the preparation of a D- alpha -amino acid from the corresponding alpha -keto acid and an amino donor with the aid of a D-transaminase, in which p-hydroxyphenylglyoxylate is contacted with a preparation of Pseudomonas putida NCIB 12565, or a mutant thereof, containing D-transaminase, in the presence of a molar excess of amino donor with respect to the p-hydroxyphenylglyoxylate, which results in optically pure D-p-hydroxyphenylglycine
Original languageEnglish
Patent numberEP0315786
Priority date17/05/86
Publication statusPublished - 1987

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