In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4(ac) epitope specificity.
|Issue number||SUPPL. 3|
|Publication status||Published - 1998|
de Geus, B., Harmsen, M., & van Zijderveld, F. (1998). Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets. Veterinary Quarterly, 20(SUPPL. 3), S87-S89.