Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets

B. de Geus; M. Harmsen; F. van Zijderveld

Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets

B. de Geus, M. Harmsen, F. van Zijderveld

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4(ac) epitope specificity.

Original language	English
Pages (from-to)	S87-S89
Journal	Veterinary Quarterly
Volume	20
Issue number	SUPPL. 3
Publication status	Published - 1998

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title = "Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets",

abstract = "In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4(ac) epitope specificity.",

author = "{de Geus}, B. and M. Harmsen and {van Zijderveld}, F.",

year = "1998",

language = "English",

volume = "20",

pages = "S87--S89",

journal = "Veterinary Quarterly",

issn = "0165-2176",

publisher = "Taylor & Francis",

number = "SUPPL. 3",

}

TY - JOUR

T1 - Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets

AU - de Geus, B.

AU - Harmsen, M.

AU - van Zijderveld, F.

PY - 1998

Y1 - 1998

N2 - In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4(ac) epitope specificity.

AB - In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4(ac) epitope specificity.

M3 - Article

VL - 20

SP - S87-S89

JO - Veterinary Quarterly

JF - Veterinary Quarterly

SN - 0165-2176

IS - SUPPL. 3

ER -