Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets

B. de Geus, M. Harmsen, F. van Zijderveld

    Research output: Contribution to journalArticleAcademicpeer-review

    9 Citations (Scopus)


    In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4(ac) epitope specificity.
    Original languageEnglish
    Pages (from-to)S87-S89
    JournalVeterinary Quarterly
    Issue numberSUPPL. 3
    Publication statusPublished - 1998


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