Prevalence of transcription factors in ascomycete and basidiomycete fungi

Richard B. Todd, Miaomiao Zhou, Robin A. Ohm, Melissa Leeggangers, Loek Visser, Ronald P. De Vries

Research output: Contribution to journalArticleAcademicpeer-review

60 Citations (Scopus)


Gene regulation underlies fungal physiology and therefore is a major factor in fungal biodiversity. Analysis of genome sequences has revealed a large number of putative transcription factors in most fungal genomes. The presence of fungal orthologs for individual regulators has been analysed and appears to be highly variable with some regulators widely conserved and others showing narrow distribution. Although genome-scale transcription factor surveys have been performed before, no global study into the prevalence of specific regulators across the fungal kingdom has been presented.
Original languageEnglish
Article number214
JournalBMC Genomics
Issue number1
Publication statusPublished - 2014

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