Prebiotics and other microbial substrates for gut functionality

A.C. Ouwehand, M.M.N. Derrien, W.M. de Vos, K. Tiihonen, N. Rautonen

Research output: Contribution to journalArticleAcademicpeer-review

119 Citations (Scopus)


The intestinal microbiota is of great importance to our health and wellbeing. Modulation of the intestinal microbiota by exogenous and endogenous substrates can be expected to improve various physiological functions of our body, not just those in the intestine. Recently, new targets such as immune function and areas outside the colon have been considered to be influenced by the intestinal microbiota. Novel approaches might include the application of prebiotics in different combinations or the provision of nutrients to different bacterial groups and to different parts of the intestine.
Original languageEnglish
Pages (from-to)212-217
JournalCurrent Opinion in Biotechnology
Issue number2
Publication statusPublished - 2005


  • chain fatty-acids
  • human-colon
  • large-intestine
  • fructo-oligosaccharides
  • anaerobic-bacteria
  • trefoil factors
  • dietary-fibers
  • fermentation
  • rat
  • inulin

Fingerprint Dive into the research topics of 'Prebiotics and other microbial substrates for gut functionality'. Together they form a unique fingerprint.

Cite this