Potential of proton-pumping rhodopsins: engineering photosystems into microorganisms

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)


A wide range of proton-pumping rhodopsins (PPRs) have been discovered in recent years. Using a synthetic biology approach, PPR photosystems with different features can be easily introduced in nonphotosynthetic microbial hosts. PPRs can provide hosts with the ability to harvest light and drive the sustainable production of biochemicals or biofuels. PPRs use light energy to generate an outward proton flux, and the resulting proton motive force can subsequently power cellular processes. Recently, the introduction of PPRs in microbial production hosts has successfully led to light-driven biotechnological conversions. In this review, we discuss relevant features of natural PPRs, evaluate reported biotechnological applications of microbial production hosts equipped with PPRs, and provide an outlook on future developments
Original languageEnglish
Pages (from-to)633-642
JournalTrends in Biotechnology
Issue number11
Publication statusPublished - 2013


  • escherichia-coli
  • functional expression
  • microbial rhodopsins
  • carbon-dioxide
  • schizosaccharomyces-pombe
  • gloeobacter rhodopsin
  • purple membrane
  • proteorhodopsin
  • bacteriorhodopsin
  • gene

Fingerprint Dive into the research topics of 'Potential of proton-pumping rhodopsins: engineering photosystems into microorganisms'. Together they form a unique fingerprint.

Cite this