Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials

Hugo Brouwer; Femke L.N. van Oijen; Hans Bouwmeester

doi:10.1016/B978-0-12-819470-6.00014-7

Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials

Hugo Brouwer, Femke L.N. van Oijen, Hans Bouwmeester

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

Abstract

A substantial part of the plastic produced worldwide ends up in the environment and degrades into nano- and microplastics. The particles are ubiquitously present in the air and enter the food production chain as contaminants. Ingestion of nano- and microplastics present in food and drinking water, or those present in swallowed lung mucus that contain trapped particles, represent the main route of human exposure. Yet much remains to be studied on the intestinal uptake by humans and the potential this exposure has to result in adverse health effects. Here we review the current knowledge and relate this to lessons learned from the field of nanotoxicology. We discuss how in vitro and in silico approaches can be used to support the risk assessment of nano- and microplastics.

Original language	English
Title of host publication	Present Knowledge in Food Safety
Subtitle of host publication	A Risk-Based Approach through the Food Chain
Editors	M.E. Knowles, L.E. Anelich, A.R. Boobis, B. Popping
Publisher	Elsevier
Chapter	40
Pages	590-605
Number of pages	16
ISBN (Electronic)	9780128194706
ISBN (Print)	9780128231548
DOIs	https://doi.org/10.1016/B978-0-12-819470-6.00014-7
Publication status	Published - 14 Oct 2022

Keywords

in vitro models
microplastics
Nanoplastics
PBK models
toxicity
uptake

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-819470-6.00014-7

Cite this

Brouwer, H., van Oijen, F. L. N., & Bouwmeester, H. (2022). Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials. In M. E. Knowles, L. E. Anelich, A. R. Boobis, & B. Popping (Eds.), Present Knowledge in Food Safety: A Risk-Based Approach through the Food Chain (pp. 590-605). Elsevier. https://doi.org/10.1016/B978-0-12-819470-6.00014-7

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Brouwer, H, van Oijen, FLN & Bouwmeester, H 2022, Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials. in ME Knowles, LE Anelich, AR Boobis & B Popping (eds), Present Knowledge in Food Safety: A Risk-Based Approach through the Food Chain. Elsevier, pp. 590-605. https://doi.org/10.1016/B978-0-12-819470-6.00014-7

Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials. / Brouwer, Hugo; van Oijen, Femke L.N.; Bouwmeester, Hans.

Present Knowledge in Food Safety: A Risk-Based Approach through the Food Chain. ed. / M.E. Knowles; L.E. Anelich; A.R. Boobis; B. Popping. Elsevier, 2022. p. 590-605.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic › peer-review

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T1 - Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials

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AB - A substantial part of the plastic produced worldwide ends up in the environment and degrades into nano- and microplastics. The particles are ubiquitously present in the air and enter the food production chain as contaminants. Ingestion of nano- and microplastics present in food and drinking water, or those present in swallowed lung mucus that contain trapped particles, represent the main route of human exposure. Yet much remains to be studied on the intestinal uptake by humans and the potential this exposure has to result in adverse health effects. Here we review the current knowledge and relate this to lessons learned from the field of nanotoxicology. We discuss how in vitro and in silico approaches can be used to support the risk assessment of nano- and microplastics.

KW - in vitro models

KW - microplastics

KW - Nanoplastics

KW - PBK models

KW - toxicity

KW - uptake

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DO - 10.1016/B978-0-12-819470-6.00014-7

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SN - 9780128231548

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EP - 605

BT - Present Knowledge in Food Safety

A2 - Knowles, M.E.

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PB - Elsevier

ER -

Potential human health effects following exposure to nano- and microplastics, lessons learned from nanomaterials

Abstract

Keywords

UN SDGs

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