Potency and control of modified live viral vaccines for veterinary use

C. Terpstra, A.H. Kroese

    Research output: Contribution to journalArticleAcademicpeer-review

    7 Citations (Scopus)

    Abstract

    This paper reviews various aspects of efficacy, and methods for assaying the potency of modified live viral vaccines. The pros and cons of parametric versus non-parametric methods for analysis of potency assays are discussed and critical levels of protection, as determined by the target(s) of vaccination, are exemplified. Recommendations are presented for designing potency assays on master virus seeds and vaccine batches.
    Original languageEnglish
    Pages (from-to)570-575
    JournalVaccine
    Volume14
    Issue number1
    DOIs
    Publication statusPublished - 1996

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