Post-Travel Screening of Asymptomatic Long-Term Travelers to the Tropics for Intestinal Parasites Using Molecular Diagnostics

D. Soonawala, L. Lieshout, M.A.M. den Boer, E.C.J. Claas, J.J. Verweij, A. Godkewitsch, M. Ratering, L.G. Visser

Research output: Contribution to journalArticleAcademicpeer-review

18 Citations (Scopus)

Abstract

The incidence of asymptomatic travel-related parasitic infection is uncertain. Previous studies did not distinguish new incident infections, from past infections. Regardless of symptoms, we performed multiplex real-time polymerase chain reaction on pre- and post-travel stool samples of Dutch long-term travelers to the (sub)tropics. Serological screening for Schistosoma spp. was only performed in travelers to sub-Saharan Africa. In total, 679 travelers were included in the study. The follow-up rate was 82% (556 of 679). Participants' median travel duration was 12 weeks. There was one incident infection with Strongyloides stercoralis; there were none with Entamoeba histolytica, 4 with Cryptosporidium spp. (1%), and 22 with Giardia lamblia (4%). Nine of 146 travelers (6%) seroconverted for Schistosoma spp. Routine screening of stool samples for parasitic infection is not indicated for asymptomatic people, who travel to the (sub)tropics for up to 3 months. Screening for Schistosoma spp. should be offered to travelers with fresh-water contact in endemic regions.
Original languageEnglish
Pages (from-to)835-839
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume90
Issue number5
DOIs
Publication statusPublished - 2014

Fingerprint

Molecular Pathology
Schistosoma
Parasites
Parasitic Diseases
Infection
Strongyloides stercoralis
Giardia lamblia
Cryptosporidium
Entamoeba histolytica
Africa South of the Sahara
Multiplex Polymerase Chain Reaction
Fresh Water
Real-Time Polymerase Chain Reaction
Incidence

Keywords

  • real-time pcr
  • strongyloides-stercoralis
  • laboratory tests
  • fecal samples
  • netherlands
  • microscopy
  • infection
  • diarrhea
  • protozoa

Cite this

Soonawala, D., Lieshout, L., den Boer, M. A. M., Claas, E. C. J., Verweij, J. J., Godkewitsch, A., ... Visser, L. G. (2014). Post-Travel Screening of Asymptomatic Long-Term Travelers to the Tropics for Intestinal Parasites Using Molecular Diagnostics. American Journal of Tropical Medicine and Hygiene, 90(5), 835-839. https://doi.org/10.4269/ajtmh.13-0594
Soonawala, D. ; Lieshout, L. ; den Boer, M.A.M. ; Claas, E.C.J. ; Verweij, J.J. ; Godkewitsch, A. ; Ratering, M. ; Visser, L.G. / Post-Travel Screening of Asymptomatic Long-Term Travelers to the Tropics for Intestinal Parasites Using Molecular Diagnostics. In: American Journal of Tropical Medicine and Hygiene. 2014 ; Vol. 90, No. 5. pp. 835-839.
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Soonawala, D, Lieshout, L, den Boer, MAM, Claas, ECJ, Verweij, JJ, Godkewitsch, A, Ratering, M & Visser, LG 2014, 'Post-Travel Screening of Asymptomatic Long-Term Travelers to the Tropics for Intestinal Parasites Using Molecular Diagnostics' American Journal of Tropical Medicine and Hygiene, vol. 90, no. 5, pp. 835-839. https://doi.org/10.4269/ajtmh.13-0594

Post-Travel Screening of Asymptomatic Long-Term Travelers to the Tropics for Intestinal Parasites Using Molecular Diagnostics. / Soonawala, D.; Lieshout, L.; den Boer, M.A.M.; Claas, E.C.J.; Verweij, J.J.; Godkewitsch, A.; Ratering, M.; Visser, L.G.

In: American Journal of Tropical Medicine and Hygiene, Vol. 90, No. 5, 2014, p. 835-839.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Verweij, J.J.

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AU - Visser, L.G.

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AB - The incidence of asymptomatic travel-related parasitic infection is uncertain. Previous studies did not distinguish new incident infections, from past infections. Regardless of symptoms, we performed multiplex real-time polymerase chain reaction on pre- and post-travel stool samples of Dutch long-term travelers to the (sub)tropics. Serological screening for Schistosoma spp. was only performed in travelers to sub-Saharan Africa. In total, 679 travelers were included in the study. The follow-up rate was 82% (556 of 679). Participants' median travel duration was 12 weeks. There was one incident infection with Strongyloides stercoralis; there were none with Entamoeba histolytica, 4 with Cryptosporidium spp. (1%), and 22 with Giardia lamblia (4%). Nine of 146 travelers (6%) seroconverted for Schistosoma spp. Routine screening of stool samples for parasitic infection is not indicated for asymptomatic people, who travel to the (sub)tropics for up to 3 months. Screening for Schistosoma spp. should be offered to travelers with fresh-water contact in endemic regions.

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KW - fecal samples

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