Post-genomics of lactic acid bacteria and other food-grade bacteria to discover gut functionality

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Abstract

Recent years have seen an explosion in the number of complete or almost complete genomic sequences of lactic acid bacteria and other food-grade bacteria that are used in functional foods to increase the health of the consumer. These have been instrumental in the development of functional, comparative and other post-genomics approaches that provide the possibility to detect, unravel and understand their functionality in the human intestinal tract. In conjunction with other high-throughput approaches, these advances can be exploited in the functional food innovation cycle for developing new or designed probiotic and other bacterial products that impact gut health.
Original languageEnglish
Pages (from-to)86-93
JournalCurrent Opinion in Biotechnology
Volume15
Issue number2
DOIs
Publication statusPublished - 2004

Keywords

  • human gastrointestinal-tract
  • signature-tagged mutagenesis
  • vivo expression technology
  • escherichia-coli k-12
  • listeria-monocytogenes
  • lactococcus-lactis
  • stress resistance
  • in-vivo
  • propionibacterium-freudenreichii
  • lactobacillus-reuteri

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