Plasma homocysteine and micro-and macrovascular complications in type 1 diabetes. A cross-sectional nested case-control study

S.S. Soedamah-Muthu, N. Chaturvedi, T. Teerlink, B. Idzior-Walus, J.H. Fuller, C.D.A. Stehouwer

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Abstract

Objectives. To examine the independent relationship between plasma total homocysteine (tHcy) and microvascular and macrovascular complications. Design. We performed a cross-sectional nested case–control study from the EURODIAB Prospective Complications Study. Setting. A hospital-based multicentre study at 24 centres in 13 European countries. Subjects. A total of 533 type 1 diabetic patients, diagnosed at
Original languageEnglish
Pages (from-to)450-459
JournalJournal of Internal Medicine
Volume258
Issue number5
DOIs
Publication statusPublished - 2005

Keywords

  • eurodiab prospective complications
  • density-lipoprotein cholesterol
  • cardiovascular-disease
  • risk-factors
  • creatinine clearance
  • endothelial function
  • insulin-resistance
  • severe retinopathy
  • albumin excretion
  • controlled trial

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