Plant cortical microtubule dynamics and cell division plane orientation

Bandan Chakrabortty

Research output: Thesisinternal PhD, WU

Abstract

This thesis work aimed at a better understanding of the molecular basis of oriented cell division in plant cell. As, the efficiency of plant morphogenesis depends on oriented cell division, this work should contribute  towards a fundamental understanding of the  molecular basis of efficient plant morphogenesis. We describe a modelling framework that allows us to simulate microtubule dynamics on the surface of arbitrary shapes. We further explored the generic role of microtubule regulatory effects  such as shape anisotropy, edge-catastrophe and enhanced microtubule stabilization on the orientation of the microtubule array. Through a  combined approach of experimental observations of cell division patterns and simulation of microtubule dynamics, we describe a possible molecular basis of oriented cell division during Arabidopsis early embryogenesis. We also infer the necessity of incorporating anisotropic growth/stress response of microtubules towards understanding division plane orientation in the growing epidermal root cells of Arabidopsis.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Scheres, Ben, Promotor
  • Mulder, Bela, Promotor
Award date30 May 2017
Place of PublicationWageningen
Publisher
Print ISBNs9789463431828
DOIs
Publication statusPublished - 2017

Fingerprint

microtubules
cell division
morphogenesis
Arabidopsis
stress response
embryogenesis
cells

Keywords

  • microtubules
  • plant cell biology
  • cell division
  • plant development
  • molecular biology
  • morphogenesis
  • simulation

Cite this

Chakrabortty, Bandan. / Plant cortical microtubule dynamics and cell division plane orientation. Wageningen : Wageningen University, 2017. 124 p.
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title = "Plant cortical microtubule dynamics and cell division plane orientation",
abstract = "This thesis work aimed at a better understanding of the molecular basis of oriented cell division in plant cell. As, the efficiency of plant morphogenesis depends on oriented cell division, this work should contribute  towards a fundamental understanding of the  molecular basis of efficient plant morphogenesis. We describe a modelling framework that allows us to simulate microtubule dynamics on the surface of arbitrary shapes. We further explored the generic role of microtubule regulatory effects  such as shape anisotropy, edge-catastrophe and enhanced microtubule stabilization on the orientation of the microtubule array. Through a  combined approach of experimental observations of cell division patterns and simulation of microtubule dynamics, we describe a possible molecular basis of oriented cell division during Arabidopsis early embryogenesis. We also infer the necessity of incorporating anisotropic growth/stress response of microtubules towards understanding division plane orientation in the growing epidermal root cells of Arabidopsis.",
keywords = "microtubules, plant cell biology, cell division, plant development, molecular biology, morphogenesis, simulation, microtubuli, plantencelbiologie, celdeling, plantenontwikkeling, moleculaire biologie, morfogenese, simulatie",
author = "Bandan Chakrabortty",
note = "WU thesis 6660 Includes bibliographical references. - With summary in English",
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doi = "10.18174/413054",
language = "English",
isbn = "9789463431828",
publisher = "Wageningen University",
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}

Chakrabortty, B 2017, 'Plant cortical microtubule dynamics and cell division plane orientation', Doctor of Philosophy, Wageningen University, Wageningen. https://doi.org/10.18174/413054

Plant cortical microtubule dynamics and cell division plane orientation. / Chakrabortty, Bandan.

Wageningen : Wageningen University, 2017. 124 p.

Research output: Thesisinternal PhD, WU

TY - THES

T1 - Plant cortical microtubule dynamics and cell division plane orientation

AU - Chakrabortty, Bandan

N1 - WU thesis 6660 Includes bibliographical references. - With summary in English

PY - 2017

Y1 - 2017

N2 - This thesis work aimed at a better understanding of the molecular basis of oriented cell division in plant cell. As, the efficiency of plant morphogenesis depends on oriented cell division, this work should contribute  towards a fundamental understanding of the  molecular basis of efficient plant morphogenesis. We describe a modelling framework that allows us to simulate microtubule dynamics on the surface of arbitrary shapes. We further explored the generic role of microtubule regulatory effects  such as shape anisotropy, edge-catastrophe and enhanced microtubule stabilization on the orientation of the microtubule array. Through a  combined approach of experimental observations of cell division patterns and simulation of microtubule dynamics, we describe a possible molecular basis of oriented cell division during Arabidopsis early embryogenesis. We also infer the necessity of incorporating anisotropic growth/stress response of microtubules towards understanding division plane orientation in the growing epidermal root cells of Arabidopsis.

AB - This thesis work aimed at a better understanding of the molecular basis of oriented cell division in plant cell. As, the efficiency of plant morphogenesis depends on oriented cell division, this work should contribute  towards a fundamental understanding of the  molecular basis of efficient plant morphogenesis. We describe a modelling framework that allows us to simulate microtubule dynamics on the surface of arbitrary shapes. We further explored the generic role of microtubule regulatory effects  such as shape anisotropy, edge-catastrophe and enhanced microtubule stabilization on the orientation of the microtubule array. Through a  combined approach of experimental observations of cell division patterns and simulation of microtubule dynamics, we describe a possible molecular basis of oriented cell division during Arabidopsis early embryogenesis. We also infer the necessity of incorporating anisotropic growth/stress response of microtubules towards understanding division plane orientation in the growing epidermal root cells of Arabidopsis.

KW - microtubules

KW - plant cell biology

KW - cell division

KW - plant development

KW - molecular biology

KW - morphogenesis

KW - simulation

KW - microtubuli

KW - plantencelbiologie

KW - celdeling

KW - plantenontwikkeling

KW - moleculaire biologie

KW - morfogenese

KW - simulatie

U2 - 10.18174/413054

DO - 10.18174/413054

M3 - internal PhD, WU

SN - 9789463431828

PB - Wageningen University

CY - Wageningen

ER -