Photoenzymatic epoxidation of styrenes

Morten M.C.H. Van Schie; Caroline E. Paul; Isabel W.C.E. Arends; Frank Hollmann

doi:10.1039/c8cc08149b

Photoenzymatic epoxidation of styrenes

Morten M.C.H. Van Schie, Caroline E. Paul, Isabel W.C.E. Arends, Frank Hollmann^*

^*Corresponding author for this work

Organic Chemistry

Research output: Contribution to journal › Article › Academic › peer-review

28 Citations (Scopus)

Abstract

Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH ₂ prosthetic group. In this contribution we provide the proof-of-concept and characterization for the direct regeneration of the styrene monooxygenase from Pseudomonas.

Original language	English
Pages (from-to)	1790-1792
Journal	Chemical Communications
Volume	55
Issue number	12
DOIs	https://doi.org/10.1039/c8cc08149b
Publication status	Published - 1 Jan 2019

Access to Document

10.1039/c8cc08149bLicence: CC BY

Cite this

@article{a470c4d908344b44a697721a3f1f5262,

title = "Photoenzymatic epoxidation of styrenes",

abstract = " Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH 2 prosthetic group. In this contribution we provide the proof-of-concept and characterization for the direct regeneration of the styrene monooxygenase from Pseudomonas. ",

author = "{Van Schie}, {Morten M.C.H.} and Paul, {Caroline E.} and Arends, {Isabel W.C.E.} and Frank Hollmann",

year = "2019",

month = jan,

day = "1",

doi = "10.1039/c8cc08149b",

language = "English",

volume = "55",

pages = "1790--1792",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "12",

}

TY - JOUR

T1 - Photoenzymatic epoxidation of styrenes

AU - Van Schie, Morten M.C.H.

AU - Paul, Caroline E.

AU - Arends, Isabel W.C.E.

AU - Hollmann, Frank

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH 2 prosthetic group. In this contribution we provide the proof-of-concept and characterization for the direct regeneration of the styrene monooxygenase from Pseudomonas.

AB - Two-component-diffusible-flavomonooxygenases are versatile biocatalysts for selective epoxidation-, hydroxylation- or halogenation reactions. Their complicated molecular architecture can be simplified using photochemical regeneration of the catalytically active, reduced FADH 2 prosthetic group. In this contribution we provide the proof-of-concept and characterization for the direct regeneration of the styrene monooxygenase from Pseudomonas.

U2 - 10.1039/c8cc08149b

DO - 10.1039/c8cc08149b

M3 - Article

C2 - 30666998

AN - SCOPUS:85061151605

SN - 1359-7345

VL - 55

SP - 1790

EP - 1792

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

Photoenzymatic epoxidation of styrenes

Abstract

Access to Document

Fingerprint

Cite this