Phospholipase A2 affects the activity of fusicoccin receptors

Patrizia Aducci*, Alessandro Ballio, Virgilio Donini, Vincenzo Fogliano, Maria Rosaria Fullone, Mauro Marra

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised receptors. Among the phospholipases tested only phospholipase A2; showed an inhibitory effect on fusicoccin binding. In particular, the influence of this enzyme on the time course and reversibility of the fusicoccin binding reaction was studied. The inhibitory effect of phospholipase A2 was the consequence of fatty acid release. The usual fatty acids of plasma membrane phospholipids were active in inhibiting the interaction of fusicoccin with its receptors. It is concluded that a phospholipid associated to the fusicoccin receptor might play a significant role in the modulation of binding.

Original languageEnglish
Pages (from-to)173-176
Number of pages4
JournalFEBS Letters
Volume320
Issue number2
DOIs
Publication statusPublished - 5 Apr 1993
Externally publishedYes

Keywords

  • Fusicoccin
  • Membrane receptor
  • Zea mays L.

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