Phospholipase A2 affects the activity of fusicoccin receptors

Patrizia Aducci; Alessandro Ballio; Virgilio Donini; Vincenzo Fogliano; Maria Rosaria Fullone; Mauro Marra

doi:10.1016/0014-5793(93)80086-A

Phospholipase A₂ affects the activity of fusicoccin receptors

Patrizia Aducci^*, Alessandro Ballio, Virgilio Donini, Vincenzo Fogliano, Maria Rosaria Fullone, Mauro Marra

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

Abstract

Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised receptors. Among the phospholipases tested only phospholipase A₂; showed an inhibitory effect on fusicoccin binding. In particular, the influence of this enzyme on the time course and reversibility of the fusicoccin binding reaction was studied. The inhibitory effect of phospholipase A₂ was the consequence of fatty acid release. The usual fatty acids of plasma membrane phospholipids were active in inhibiting the interaction of fusicoccin with its receptors. It is concluded that a phospholipid associated to the fusicoccin receptor might play a significant role in the modulation of binding.

Original language	English
Pages (from-to)	173-176
Number of pages	4
Journal	FEBS Letters
Volume	320
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(93)80086-A
Publication status	Published - 5 Apr 1993
Externally published	Yes

Keywords

Fusicoccin
Membrane receptor
Zea mays L.

Access to Document

10.1016/0014-5793(93)80086-ALicence: Publisher

Cite this

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title = "Phospholipase A2 affects the activity of fusicoccin receptors",

abstract = "Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised receptors. Among the phospholipases tested only phospholipase A2; showed an inhibitory effect on fusicoccin binding. In particular, the influence of this enzyme on the time course and reversibility of the fusicoccin binding reaction was studied. The inhibitory effect of phospholipase A2 was the consequence of fatty acid release. The usual fatty acids of plasma membrane phospholipids were active in inhibiting the interaction of fusicoccin with its receptors. It is concluded that a phospholipid associated to the fusicoccin receptor might play a significant role in the modulation of binding.",

keywords = "Fusicoccin, Membrane receptor, Zea mays L.",

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T1 - Phospholipase A2 affects the activity of fusicoccin receptors

AU - Aducci, Patrizia

AU - Ballio, Alessandro

AU - Donini, Virgilio

AU - Fogliano, Vincenzo

AU - Fullone, Maria Rosaria

AU - Marra, Mauro

PY - 1993/4/5

Y1 - 1993/4/5

N2 - Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised receptors. Among the phospholipases tested only phospholipase A2; showed an inhibitory effect on fusicoccin binding. In particular, the influence of this enzyme on the time course and reversibility of the fusicoccin binding reaction was studied. The inhibitory effect of phospholipase A2 was the consequence of fatty acid release. The usual fatty acids of plasma membrane phospholipids were active in inhibiting the interaction of fusicoccin with its receptors. It is concluded that a phospholipid associated to the fusicoccin receptor might play a significant role in the modulation of binding.

AB - Biochemical properties of fusicoccin receptors are strongly influenced by the phospholipid environment. In this report we have studied the effect of different exogenous phospholipases on fusicoccin binding ability of both plasma membrane and solubilised receptors. Among the phospholipases tested only phospholipase A2; showed an inhibitory effect on fusicoccin binding. In particular, the influence of this enzyme on the time course and reversibility of the fusicoccin binding reaction was studied. The inhibitory effect of phospholipase A2 was the consequence of fatty acid release. The usual fatty acids of plasma membrane phospholipids were active in inhibiting the interaction of fusicoccin with its receptors. It is concluded that a phospholipid associated to the fusicoccin receptor might play a significant role in the modulation of binding.

KW - Fusicoccin

KW - Membrane receptor

KW - Zea mays L.

U2 - 10.1016/0014-5793(93)80086-A

DO - 10.1016/0014-5793(93)80086-A

M3 - Article

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