Periprandial changes of the sympathetic-parasympathetic balance related to perceived satiety in humans

L.F. Harthoorn, E. Dransfield

    Research output: Contribution to journalArticleAcademicpeer-review

    35 Citations (Scopus)

    Abstract

    Food intake regulation involves various central and peripheral mechanisms. In this study the relevance of physiological responses reflecting the autonomic nervous system were evaluated in relation to perceived satiety. Subjects were exposed to a lunch-induced hunger-satiety shift, while profiling diverse sensory, physiological, and biochemical characteristics at 15 min intervals. Sensory ratings comprised questionnaires with visual analogues scales about their feeling of satiety, desire to eat, fullness, and hunger. Physiological characteristics included heart rate, heart rate variability, and blood pressure, while biochemical markers such as cortisol levels and ¿-amylase activity were monitored in saliva. The four sensory ratings correlated with heart rate and salivary ¿-amylase suggesting a higher sympathetic tone during satiety. Furthermore, heart rate variability was associated with age and waist-to-hip ratio and cortisol levels negatively correlated with body mass index. Finally, neither chewing nor swallowing contributed to a heart rate increase at food consumption, but orosensory stimulation, as tested with modified sham feeding, caused a partial increase of heart rate. In conclusion, after meal ingestion critical physiological alterations reveal a elevated sympathetic tone, which is a potential measure of satiety.
    Original languageEnglish
    Pages (from-to)601-608
    JournalEuropean Journal of Applied Physiology
    Volume102
    Issue number5
    DOIs
    Publication statusPublished - 2008

    Fingerprint

    Heart Rate
    Hunger
    Amylases
    Hydrocortisone
    Appetite Regulation
    Lunch
    Waist-Hip Ratio
    Mastication
    Autonomic Nervous System
    Deglutition
    Visual Analog Scale
    Saliva
    Meals
    Emotions
    Body Mass Index
    Eating
    Biomarkers
    Blood Pressure
    Food

    Keywords

    • melanin-concentrating hormone
    • salivary alpha-amylase
    • heart-rate-variability
    • food-intake
    • melanocortin system
    • spectral-analysis
    • cephalic phase
    • responses
    • obesity
    • appetite

    Cite this

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    title = "Periprandial changes of the sympathetic-parasympathetic balance related to perceived satiety in humans",
    abstract = "Food intake regulation involves various central and peripheral mechanisms. In this study the relevance of physiological responses reflecting the autonomic nervous system were evaluated in relation to perceived satiety. Subjects were exposed to a lunch-induced hunger-satiety shift, while profiling diverse sensory, physiological, and biochemical characteristics at 15 min intervals. Sensory ratings comprised questionnaires with visual analogues scales about their feeling of satiety, desire to eat, fullness, and hunger. Physiological characteristics included heart rate, heart rate variability, and blood pressure, while biochemical markers such as cortisol levels and ¿-amylase activity were monitored in saliva. The four sensory ratings correlated with heart rate and salivary ¿-amylase suggesting a higher sympathetic tone during satiety. Furthermore, heart rate variability was associated with age and waist-to-hip ratio and cortisol levels negatively correlated with body mass index. Finally, neither chewing nor swallowing contributed to a heart rate increase at food consumption, but orosensory stimulation, as tested with modified sham feeding, caused a partial increase of heart rate. In conclusion, after meal ingestion critical physiological alterations reveal a elevated sympathetic tone, which is a potential measure of satiety.",
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    Periprandial changes of the sympathetic-parasympathetic balance related to perceived satiety in humans. / Harthoorn, L.F.; Dransfield, E.

    In: European Journal of Applied Physiology, Vol. 102, No. 5, 2008, p. 601-608.

    Research output: Contribution to journalArticleAcademicpeer-review

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    AU - Harthoorn, L.F.

    AU - Dransfield, E.

    PY - 2008

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    N2 - Food intake regulation involves various central and peripheral mechanisms. In this study the relevance of physiological responses reflecting the autonomic nervous system were evaluated in relation to perceived satiety. Subjects were exposed to a lunch-induced hunger-satiety shift, while profiling diverse sensory, physiological, and biochemical characteristics at 15 min intervals. Sensory ratings comprised questionnaires with visual analogues scales about their feeling of satiety, desire to eat, fullness, and hunger. Physiological characteristics included heart rate, heart rate variability, and blood pressure, while biochemical markers such as cortisol levels and ¿-amylase activity were monitored in saliva. The four sensory ratings correlated with heart rate and salivary ¿-amylase suggesting a higher sympathetic tone during satiety. Furthermore, heart rate variability was associated with age and waist-to-hip ratio and cortisol levels negatively correlated with body mass index. Finally, neither chewing nor swallowing contributed to a heart rate increase at food consumption, but orosensory stimulation, as tested with modified sham feeding, caused a partial increase of heart rate. In conclusion, after meal ingestion critical physiological alterations reveal a elevated sympathetic tone, which is a potential measure of satiety.

    AB - Food intake regulation involves various central and peripheral mechanisms. In this study the relevance of physiological responses reflecting the autonomic nervous system were evaluated in relation to perceived satiety. Subjects were exposed to a lunch-induced hunger-satiety shift, while profiling diverse sensory, physiological, and biochemical characteristics at 15 min intervals. Sensory ratings comprised questionnaires with visual analogues scales about their feeling of satiety, desire to eat, fullness, and hunger. Physiological characteristics included heart rate, heart rate variability, and blood pressure, while biochemical markers such as cortisol levels and ¿-amylase activity were monitored in saliva. The four sensory ratings correlated with heart rate and salivary ¿-amylase suggesting a higher sympathetic tone during satiety. Furthermore, heart rate variability was associated with age and waist-to-hip ratio and cortisol levels negatively correlated with body mass index. Finally, neither chewing nor swallowing contributed to a heart rate increase at food consumption, but orosensory stimulation, as tested with modified sham feeding, caused a partial increase of heart rate. In conclusion, after meal ingestion critical physiological alterations reveal a elevated sympathetic tone, which is a potential measure of satiety.

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