Periconceptional maternal ‘high fish and olive oil, low meat’ dietary pattern is associated with increased embryonic growth

The Rotterdam Periconceptional Cohort (Predict) Study

F. Parisi, M. Rousian, N.A. Huijgen, A.H.J. Koning, S.P. Willemsen, J.H.M. de Vries, I. Cetin, E.A.P. Steegers, R.P.M. Steegers-Theunissen

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Abstract

Objective: To investigate the association between periconceptional maternal dietary pattern and first-trimester embryonic growth. Methods: This was a prospective cohort study of 228 women with a singleton ongoing pregnancy, of which 135 were strictly dated spontaneous pregnancies and 93 were pregnancies achieved after in-vitro fertilization or intracytoplasmatic sperm injection (IVF/ICSI). All women underwent serial transvaginal three-dimensional ultrasound (3D-US) examinations from 6 + 0 to 13 + 0 weeks' gestation. Crown–rump length (CRL) and embryonic volume (EV) measurements were performed using a virtual reality system. Information on periconceptional maternal dietary intake was collected via food frequency questionnaires. Principal component analysis was performed to identify dietary patterns. Associations between dietary patterns and CRL and EV trajectories were investigated using linear mixed models adjusted for potential confounders. Results: A median of five (range, one to seven) 3D-US scans per pregnancy were performed. Of 1162 datasets, quality was sufficient to perform CRL measurements in 991 (85.3%) and EV measurements in 899 (77.4%). A dietary pattern comprising high intake of fish and olive oil and a very low intake of meat was identified as beneficial for embryonic growth. In strictly dated spontaneous pregnancies, strong adherence to the ‘high fish and olive oil, low meat’ dietary pattern was associated with a 1.9 mm (95% CI, 0.1–3.63 mm) increase in CRL (+14.6%) at 7 weeks and a 3.4 mm (95% CI, 0.2–7.81 mm) increase (+6.9%) at 11 weeks, whereas EV increased by 0.06 cm3 (95% CI, 0.01–0.13 cm3) (+20.4%) at 7 weeks and 1.43 cm3 (95% CI, 0.99–1.87 cm3) (+14.4%) at 11 weeks. No significant association was observed in the total study population or in the IVF/ICSI subgroup. Conclusion: Periconceptional maternal adherence to a high fish and olive oil, low meat dietary pattern is positively associated with embryonic growth in spontaneously conceived pregnancies.
Original languageEnglish
Pages (from-to)709-716
JournalUltrasound in Obstetrics and Gynecology
Volume50
Issue number6
DOIs
Publication statusPublished - 1 Dec 2017

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Fish Oils
Meat
Cohort Studies
Mothers
Pregnancy
Growth
Fertilization in Vitro
Spermatozoa
User-Computer Interface
Injections
First Pregnancy Trimester
Olive Oil
Principal Component Analysis
Linear Models
Prospective Studies
Food
Population

Keywords

  • 3D ultrasound
  • crown–rump length
  • embryonic volume
  • first trimester
  • maternal dietary patterns
  • periconceptional period
  • virtual reality

Cite this

Parisi, F. ; Rousian, M. ; Huijgen, N.A. ; Koning, A.H.J. ; Willemsen, S.P. ; de Vries, J.H.M. ; Cetin, I. ; Steegers, E.A.P. ; Steegers-Theunissen, R.P.M. / Periconceptional maternal ‘high fish and olive oil, low meat’ dietary pattern is associated with increased embryonic growth : The Rotterdam Periconceptional Cohort (Predict) Study. In: Ultrasound in Obstetrics and Gynecology. 2017 ; Vol. 50, No. 6. pp. 709-716.
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title = "Periconceptional maternal ‘high fish and olive oil, low meat’ dietary pattern is associated with increased embryonic growth: The Rotterdam Periconceptional Cohort (Predict) Study",
abstract = "Objective: To investigate the association between periconceptional maternal dietary pattern and first-trimester embryonic growth. Methods: This was a prospective cohort study of 228 women with a singleton ongoing pregnancy, of which 135 were strictly dated spontaneous pregnancies and 93 were pregnancies achieved after in-vitro fertilization or intracytoplasmatic sperm injection (IVF/ICSI). All women underwent serial transvaginal three-dimensional ultrasound (3D-US) examinations from 6 + 0 to 13 + 0 weeks' gestation. Crown–rump length (CRL) and embryonic volume (EV) measurements were performed using a virtual reality system. Information on periconceptional maternal dietary intake was collected via food frequency questionnaires. Principal component analysis was performed to identify dietary patterns. Associations between dietary patterns and CRL and EV trajectories were investigated using linear mixed models adjusted for potential confounders. Results: A median of five (range, one to seven) 3D-US scans per pregnancy were performed. Of 1162 datasets, quality was sufficient to perform CRL measurements in 991 (85.3{\%}) and EV measurements in 899 (77.4{\%}). A dietary pattern comprising high intake of fish and olive oil and a very low intake of meat was identified as beneficial for embryonic growth. In strictly dated spontaneous pregnancies, strong adherence to the ‘high fish and olive oil, low meat’ dietary pattern was associated with a 1.9 mm (95{\%} CI, 0.1–3.63 mm) increase in CRL (+14.6{\%}) at 7 weeks and a 3.4 mm (95{\%} CI, 0.2–7.81 mm) increase (+6.9{\%}) at 11 weeks, whereas EV increased by 0.06 cm3 (95{\%} CI, 0.01–0.13 cm3) (+20.4{\%}) at 7 weeks and 1.43 cm3 (95{\%} CI, 0.99–1.87 cm3) (+14.4{\%}) at 11 weeks. No significant association was observed in the total study population or in the IVF/ICSI subgroup. Conclusion: Periconceptional maternal adherence to a high fish and olive oil, low meat dietary pattern is positively associated with embryonic growth in spontaneously conceived pregnancies.",
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author = "F. Parisi and M. Rousian and N.A. Huijgen and A.H.J. Koning and S.P. Willemsen and {de Vries}, J.H.M. and I. Cetin and E.A.P. Steegers and R.P.M. Steegers-Theunissen",
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Periconceptional maternal ‘high fish and olive oil, low meat’ dietary pattern is associated with increased embryonic growth : The Rotterdam Periconceptional Cohort (Predict) Study. / Parisi, F.; Rousian, M.; Huijgen, N.A.; Koning, A.H.J.; Willemsen, S.P.; de Vries, J.H.M.; Cetin, I.; Steegers, E.A.P.; Steegers-Theunissen, R.P.M.

In: Ultrasound in Obstetrics and Gynecology, Vol. 50, No. 6, 01.12.2017, p. 709-716.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Periconceptional maternal ‘high fish and olive oil, low meat’ dietary pattern is associated with increased embryonic growth

T2 - The Rotterdam Periconceptional Cohort (Predict) Study

AU - Parisi, F.

AU - Rousian, M.

AU - Huijgen, N.A.

AU - Koning, A.H.J.

AU - Willemsen, S.P.

AU - de Vries, J.H.M.

AU - Cetin, I.

AU - Steegers, E.A.P.

AU - Steegers-Theunissen, R.P.M.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Objective: To investigate the association between periconceptional maternal dietary pattern and first-trimester embryonic growth. Methods: This was a prospective cohort study of 228 women with a singleton ongoing pregnancy, of which 135 were strictly dated spontaneous pregnancies and 93 were pregnancies achieved after in-vitro fertilization or intracytoplasmatic sperm injection (IVF/ICSI). All women underwent serial transvaginal three-dimensional ultrasound (3D-US) examinations from 6 + 0 to 13 + 0 weeks' gestation. Crown–rump length (CRL) and embryonic volume (EV) measurements were performed using a virtual reality system. Information on periconceptional maternal dietary intake was collected via food frequency questionnaires. Principal component analysis was performed to identify dietary patterns. Associations between dietary patterns and CRL and EV trajectories were investigated using linear mixed models adjusted for potential confounders. Results: A median of five (range, one to seven) 3D-US scans per pregnancy were performed. Of 1162 datasets, quality was sufficient to perform CRL measurements in 991 (85.3%) and EV measurements in 899 (77.4%). A dietary pattern comprising high intake of fish and olive oil and a very low intake of meat was identified as beneficial for embryonic growth. In strictly dated spontaneous pregnancies, strong adherence to the ‘high fish and olive oil, low meat’ dietary pattern was associated with a 1.9 mm (95% CI, 0.1–3.63 mm) increase in CRL (+14.6%) at 7 weeks and a 3.4 mm (95% CI, 0.2–7.81 mm) increase (+6.9%) at 11 weeks, whereas EV increased by 0.06 cm3 (95% CI, 0.01–0.13 cm3) (+20.4%) at 7 weeks and 1.43 cm3 (95% CI, 0.99–1.87 cm3) (+14.4%) at 11 weeks. No significant association was observed in the total study population or in the IVF/ICSI subgroup. Conclusion: Periconceptional maternal adherence to a high fish and olive oil, low meat dietary pattern is positively associated with embryonic growth in spontaneously conceived pregnancies.

AB - Objective: To investigate the association between periconceptional maternal dietary pattern and first-trimester embryonic growth. Methods: This was a prospective cohort study of 228 women with a singleton ongoing pregnancy, of which 135 were strictly dated spontaneous pregnancies and 93 were pregnancies achieved after in-vitro fertilization or intracytoplasmatic sperm injection (IVF/ICSI). All women underwent serial transvaginal three-dimensional ultrasound (3D-US) examinations from 6 + 0 to 13 + 0 weeks' gestation. Crown–rump length (CRL) and embryonic volume (EV) measurements were performed using a virtual reality system. Information on periconceptional maternal dietary intake was collected via food frequency questionnaires. Principal component analysis was performed to identify dietary patterns. Associations between dietary patterns and CRL and EV trajectories were investigated using linear mixed models adjusted for potential confounders. Results: A median of five (range, one to seven) 3D-US scans per pregnancy were performed. Of 1162 datasets, quality was sufficient to perform CRL measurements in 991 (85.3%) and EV measurements in 899 (77.4%). A dietary pattern comprising high intake of fish and olive oil and a very low intake of meat was identified as beneficial for embryonic growth. In strictly dated spontaneous pregnancies, strong adherence to the ‘high fish and olive oil, low meat’ dietary pattern was associated with a 1.9 mm (95% CI, 0.1–3.63 mm) increase in CRL (+14.6%) at 7 weeks and a 3.4 mm (95% CI, 0.2–7.81 mm) increase (+6.9%) at 11 weeks, whereas EV increased by 0.06 cm3 (95% CI, 0.01–0.13 cm3) (+20.4%) at 7 weeks and 1.43 cm3 (95% CI, 0.99–1.87 cm3) (+14.4%) at 11 weeks. No significant association was observed in the total study population or in the IVF/ICSI subgroup. Conclusion: Periconceptional maternal adherence to a high fish and olive oil, low meat dietary pattern is positively associated with embryonic growth in spontaneously conceived pregnancies.

KW - 3D ultrasound

KW - crown–rump length

KW - embryonic volume

KW - first trimester

KW - maternal dietary patterns

KW - periconceptional period

KW - virtual reality

U2 - 10.1002/uog.17408

DO - 10.1002/uog.17408

M3 - Article

VL - 50

SP - 709

EP - 716

JO - Ultrasound in Obstetrics and Gynecology

JF - Ultrasound in Obstetrics and Gynecology

SN - 0960-7692

IS - 6

ER -