Abstract
In the study of large outbred pedigrees with many founders, individual bi-allelic markers, such as SNP markers, carry little information. After phasing the marker genotypes, multi-allelic loci consisting of groups of closely linked markers can be identified, which are called “haploblocks”. Here, we describe PediHaplotyper, an R package capable of assigning consistent alleles to such haploblocks, allowing for missing and incorrect SNP data. These haploblock genotypes are much easier to interpret by the human investigator than the original SNP data and also allow more efficient QTL analyses that require less memory and computation time.
Original language | English |
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Article number | 119 |
Journal | Molecular Breeding |
Volume | 36 |
DOIs | |
Publication status | Published - 2016 |
Keywords
- Haploblock
- Haplotyping
- Pedigree
- SNP