Parameters for natural resistance in bovine milk

T.C.W. Ploegaert

Research output: Thesisinternal PhD, WUAcademic

Abstract

Parameters for natural resistance in bovine milk
Mastitis or udder inflammation is one of the most important health problems of dairy cattle. Resistance against mastitis and many other diseases is partly based on the naturally present disease resistance capacity: innate immunity. This research therefore aimed to identify adequate immune parameters and determine their relation with the susceptibility of the individual animal for mastitis and possibly also other health problems. Natural antibodies (NAb) were found suitable to further study their relation with natural resistance of dairy cows. Heritability of NAb in milk samples of heifers (cows that had a calf for the first time) was low to moderate, which gives potential for genetic selection. It should, however, be investigated if selection for improved NAb levels has unintentionally also negative relations with other selection traits. Furthermore, NAb could also be influenced by management factors, but this would be a subject for future study. Besides, results suggested that higher levels of certain NAb in milk can decrease the risk for high Somatic Cell Count (in heifers), clinical mastitis and genital organ and fertility problems. However, heifers appear to differ from older cows in the relation of their NAb levels with risk for CM and high SCC, and the (udder) health history also affects this relation.
LanguageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wageningen University
Supervisors/Advisors
  • Savelkoul, Huub, Promotor
  • van Arendonk, Johan, Promotor
  • Tijhaar, Edwin, Co-promotor
Award date14 Dec 2010
Place of Publication[S.l.
Publisher
Print ISBNs9789085858270
Publication statusPublished - 2010

Fingerprint

milk
antibodies
mastitis
heifers
udders
cows
somatic cell count
genitalia
dairy cattle
disease resistance
heritability
dairy cows
inflammation
calves
history
animals
sampling

Keywords

  • dairy cows
  • holstein-friesian
  • milk
  • bovine mastitis
  • resistance
  • immune system
  • immunity
  • natural antibodies
  • genetic variation
  • immunology
  • animal health

Cite this

Ploegaert, T. C. W. (2010). Parameters for natural resistance in bovine milk. [S.l.: S.n.
Ploegaert, T.C.W.. / Parameters for natural resistance in bovine milk. [S.l. : S.n., 2010. 143 p.
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title = "Parameters for natural resistance in bovine milk",
abstract = "Parameters for natural resistance in bovine milk Mastitis or udder inflammation is one of the most important health problems of dairy cattle. Resistance against mastitis and many other diseases is partly based on the naturally present disease resistance capacity: innate immunity. This research therefore aimed to identify adequate immune parameters and determine their relation with the susceptibility of the individual animal for mastitis and possibly also other health problems. Natural antibodies (NAb) were found suitable to further study their relation with natural resistance of dairy cows. Heritability of NAb in milk samples of heifers (cows that had a calf for the first time) was low to moderate, which gives potential for genetic selection. It should, however, be investigated if selection for improved NAb levels has unintentionally also negative relations with other selection traits. Furthermore, NAb could also be influenced by management factors, but this would be a subject for future study. Besides, results suggested that higher levels of certain NAb in milk can decrease the risk for high Somatic Cell Count (in heifers), clinical mastitis and genital organ and fertility problems. However, heifers appear to differ from older cows in the relation of their NAb levels with risk for CM and high SCC, and the (udder) health history also affects this relation.",
keywords = "melkkoeien, zwartbont, melk, rundermastitis, weerstand, immuunsysteem, immuniteit, natuurlijke antilichamen, genetische variatie, immunologie, diergezondheid, dairy cows, holstein-friesian, milk, bovine mastitis, resistance, immune system, immunity, natural antibodies, genetic variation, immunology, animal health",
author = "T.C.W. Ploegaert",
note = "WU thesis 4962",
year = "2010",
language = "English",
isbn = "9789085858270",
publisher = "S.n.",
school = "Wageningen University",

}

Ploegaert, TCW 2010, 'Parameters for natural resistance in bovine milk', Doctor of Philosophy, Wageningen University, [S.l..

Parameters for natural resistance in bovine milk. / Ploegaert, T.C.W.

[S.l. : S.n., 2010. 143 p.

Research output: Thesisinternal PhD, WUAcademic

TY - THES

T1 - Parameters for natural resistance in bovine milk

AU - Ploegaert, T.C.W.

N1 - WU thesis 4962

PY - 2010

Y1 - 2010

N2 - Parameters for natural resistance in bovine milk Mastitis or udder inflammation is one of the most important health problems of dairy cattle. Resistance against mastitis and many other diseases is partly based on the naturally present disease resistance capacity: innate immunity. This research therefore aimed to identify adequate immune parameters and determine their relation with the susceptibility of the individual animal for mastitis and possibly also other health problems. Natural antibodies (NAb) were found suitable to further study their relation with natural resistance of dairy cows. Heritability of NAb in milk samples of heifers (cows that had a calf for the first time) was low to moderate, which gives potential for genetic selection. It should, however, be investigated if selection for improved NAb levels has unintentionally also negative relations with other selection traits. Furthermore, NAb could also be influenced by management factors, but this would be a subject for future study. Besides, results suggested that higher levels of certain NAb in milk can decrease the risk for high Somatic Cell Count (in heifers), clinical mastitis and genital organ and fertility problems. However, heifers appear to differ from older cows in the relation of their NAb levels with risk for CM and high SCC, and the (udder) health history also affects this relation.

AB - Parameters for natural resistance in bovine milk Mastitis or udder inflammation is one of the most important health problems of dairy cattle. Resistance against mastitis and many other diseases is partly based on the naturally present disease resistance capacity: innate immunity. This research therefore aimed to identify adequate immune parameters and determine their relation with the susceptibility of the individual animal for mastitis and possibly also other health problems. Natural antibodies (NAb) were found suitable to further study their relation with natural resistance of dairy cows. Heritability of NAb in milk samples of heifers (cows that had a calf for the first time) was low to moderate, which gives potential for genetic selection. It should, however, be investigated if selection for improved NAb levels has unintentionally also negative relations with other selection traits. Furthermore, NAb could also be influenced by management factors, but this would be a subject for future study. Besides, results suggested that higher levels of certain NAb in milk can decrease the risk for high Somatic Cell Count (in heifers), clinical mastitis and genital organ and fertility problems. However, heifers appear to differ from older cows in the relation of their NAb levels with risk for CM and high SCC, and the (udder) health history also affects this relation.

KW - melkkoeien

KW - zwartbont

KW - melk

KW - rundermastitis

KW - weerstand

KW - immuunsysteem

KW - immuniteit

KW - natuurlijke antilichamen

KW - genetische variatie

KW - immunologie

KW - diergezondheid

KW - dairy cows

KW - holstein-friesian

KW - milk

KW - bovine mastitis

KW - resistance

KW - immune system

KW - immunity

KW - natural antibodies

KW - genetic variation

KW - immunology

KW - animal health

M3 - internal PhD, WU

SN - 9789085858270

PB - S.n.

CY - [S.l.

ER -

Ploegaert TCW. Parameters for natural resistance in bovine milk. [S.l.: S.n., 2010. 143 p.