PanTools v3: functional annotation, classification and phylogenomics

E.M. Jonkheer*, F.J.M. van Workum, S. Sheikhizadeh Anari, B. Brankovics, J.R. de Haan, Lidija Berke, T.A.J. van der Lee, D. de Ridder, S. Smit*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


The ever-increasing number of sequenced genomes necessitates the development of pangenomic approaches for comparative genomics. Introduced in 2016, PanTools is a platform that allows pangenome construction, homology grouping and pangenomic read mapping. The use of graph database technology makes PanTools versatile, applicable from small viral genomes like SARS-CoV-2 up to large plant or animal genomes like tomato or human. Here, we present our third major update to PanTools that enables the integration of functional annotations and provides both gene-level analyses and phylogenetics.
Original languageEnglish
Pages (from-to)4403-4405
Issue number18
Publication statusPublished - 15 Sep 2022


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