Pan-European modelling of consumer exposure to toxic compounds present in food

J.D. van Klaveren, K. Svensson, C. Brera

    Research output: Contribution to journalAbstractAcademic

    Abstract

    As part of the EU sixth framework project SAFE FOODS an electronic platform of food consumption and residue databases from different EU countries (Netherlands, Sweden, Denmark, Czech Republic, and Italy) has been built. The coding of the data has been harmonised, making it possible to perform probabilistic exposure assessments in a harmonised way and to merge or exchange data between countries. This electronic platform forms a powerful tool to calculate dietary exposure to chemicals using data from different countries and can be viewed as a prototype of how data sharing within Europe could be organised. The probabilistic software used is the Monte Carlo Risk Assessment (MCRA) software. MCRA makes use of the whole food consumption and residue database. Short-term and long-term intake calculations can be made comparing results with acute and chronic toxic endpoints. MCRA-software(www.mcra.rikilt.wur.nl) and the databases are internet-compatible and can be used from everywhere in the world. Within the SAFE FOODS project calculations are made for pesticides, mycotoxins and natural toxins. Differences in results between countries are a consequence of differences in occurrence data and/or differences in food consumption habits per country. An important part of data sharing is the check on data quality. Quality parameters of the analytical methods and sampling procedures are considered in the data sharing process. Presently, the electronic platform is used to address questions raised by EFSA, while other stakeholders also have expressed their interest. This platform has a great potential to facilitate more realistic exposure assessments at the pan-European level.
    Original languageEnglish
    Pages (from-to)S109-S110
    JournalToxicology Letters
    Volume172
    Issue numberSuppl.1
    DOIs
    Publication statusPublished - 2007

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