One after the other: A novel Bluetongue virus strain related to Toggenburg virus detected in the Piedmont region (North-western Italy), extends the panel of novel atypical BTV strains

Maurilia Marcacci, Serena Sant, Iolanda Mangone, Maria Goria, Alessandro Dondo, Simona Zoppi, René G.P. van Gennip, Maria Cristina Radaelli, Cesare Cammà, Piet A. van Rijn, Giovanni Savini, Alessio Lorusso*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)

Abstract

In this rapid communication, a novel atypical bluetongue virus (BTV) strain detected in goats in the Piedmont region (north-western Italy) is described. This strain, BTV-Z ITA2017, is most related in Seg-2/VP-2 (83.8% nt/82.7% aa) to strain TOV of BTV-25. Reactive antisera of goats positive by cELISA for BTV antibodies failed to neutralize a chimeric virus expressing the outermost protein of TOV. Infected animals displayed low levels of RNAemia and absence of clinical signs consistent with bluetongue infection, a scenario described in animals infected with atypical BTV strains.
Original languageEnglish
Pages (from-to)370-374
JournalTransboundary and Emerging Diseases
Volume65
Issue number2
Early online date2018
DOIs
Publication statusPublished - Apr 2018

Keywords

  • Arboviruses
  • Diagnostics
  • Emerging diseases
  • Virus

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