Obstacles to vaccination of animals and prospective solutions

Anja Holm, Jeroen Kortekaas*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

On the 17th of October 2019, a workshop was held at Wageningen Bioveterinary Research in Lelystad, the Netherlands, to discuss the obstacles to vaccination in the veterinary field. Participants from academia, OIE, FAO, EC, EMA, USDA, national regulatory and veterinary health authorities, and the animal health industry discussed how availability and access to animal vaccines can be improved not just in the EU and US but also in Low to Middle Income Countries (LMIC) across the world and agreed that this requires innovations in both the scientific and the regulatory field. The workshop called for engaging all stakeholders to improve regulatory acceptance of novel vaccine technologies and encourage their registration. There is a need for better mutual understanding between academia, industry and regulators, and more openness to discuss framework, requirements, and product authorisations, and to converge the regulatory rules between regions. The next leap forward could be a broader application of novel technologies using RNA- or DNA-based vaccine platforms, where the “backbone” is maintained, while the gene of interest coding for an immunogenic protein can be exchanged in a standardised manner. This approach enables rapid response in outbreak situations and should lower the risk and cost of vaccine development.

Original languageEnglish
Pages (from-to)46-49
JournalBiologicals
Volume65
Early online date21 Mar 2020
DOIs
Publication statusPublished - May 2020

Keywords

  • Emerging animal diseases
  • Obstacles to vaccination
  • Regulatory acceptance
  • Vaccine platforms
  • Veterinary

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