Nutrikinetic assessment of polyphenol exposure

John van Duynhoven, Ewoud J.J. Van Velzen, Doris Maria Jacobs

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

The key to link intake of polyphenols to health benefits is the quantitative and kinetic assessment of their metabolites in circulation. Current analytical approaches have only provided limited quantitative coverage of the internal polyphenol metabolome, this in particular pertains to conjugated microbial catabolites. Current modelling approaches to describe the kinetic appearance of polyphenol metabolites into circulation mostly neglect the multi-compartment nature of polyphenol metabolism in the body. Furthermore, inter-individual variation is mostly neglected in current modelling approaches. These gaps hamper clear definition of the modulating effects of metabotypes and food matrix on the internal polyphenol metabolome.

Original languageEnglish
Pages (from-to)88-95
JournalCurrent Opinion in Food Science
Volume16
DOIs
Publication statusPublished - 2017

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Polyphenols
polyphenols
metabolome
Metabolome
metabolites
kinetics
food matrix
Insurance Benefits
Food
metabolism

Cite this

van Duynhoven, John ; Van Velzen, Ewoud J.J. ; Jacobs, Doris Maria. / Nutrikinetic assessment of polyphenol exposure. In: Current Opinion in Food Science. 2017 ; Vol. 16. pp. 88-95.
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Nutrikinetic assessment of polyphenol exposure. / van Duynhoven, John; Van Velzen, Ewoud J.J.; Jacobs, Doris Maria.

In: Current Opinion in Food Science, Vol. 16, 2017, p. 88-95.

Research output: Contribution to journalArticleAcademicpeer-review

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SN - 2214-7993

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