Nutrient-gene interactions in benefit-risk analysis

J. Hesketh, I. Wybranska, Y.E.M. Dommels, M. King, R. Elliot, C. Pico, J. Keijer

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)

Abstract

Individuals respond differently to nutrients and foods. This is reflected in different levels of benefits and risks at the same intake of a nutrient and, consequently, different `windows of benefit' in terms of nutrient intake. This has led recently to the concept of `personalised nutrition'. Genetic factors such as single nucleotide polymorphisms may be one source of this inter-individual variation in benefit¿risk response to nutrients. In 2004 a European Union-funded network of excellence in the area of nutrigenomics (European Nutrigenomics Organisation; NuGO) organised a workshop on the role of nutrient¿gene interactions in determining benefit¿risk of nutrients and diet. The major issues discussed at the workshop are presented in the present paper and highlighted with examples from the presentations. The overall consensus was that although genetics provides a new vision where genetic information could in the future be used to provide knowledge on disease predisposition and nutritional requirements, such a goal is still far off and much more research is required before we can reliably include genetic factors in the risk¿benefit assessment of nutrients and diets
LanguageEnglish
Pages1232-1236
JournalBritish Journal of Nutrition
Volume95
Issue number6
DOIs
Publication statusPublished - 2006

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Food
Genes
Nutrigenomics
Diet
Education
Nutritional Requirements
European Union
Single Nucleotide Polymorphism
Organizations
Research

Cite this

Hesketh, J., Wybranska, I., Dommels, Y. E. M., King, M., Elliot, R., Pico, C., & Keijer, J. (2006). Nutrient-gene interactions in benefit-risk analysis. British Journal of Nutrition, 95(6), 1232-1236. https://doi.org/10.1079/BJN20061749
Hesketh, J. ; Wybranska, I. ; Dommels, Y.E.M. ; King, M. ; Elliot, R. ; Pico, C. ; Keijer, J. / Nutrient-gene interactions in benefit-risk analysis. In: British Journal of Nutrition. 2006 ; Vol. 95, No. 6. pp. 1232-1236.
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Hesketh, J, Wybranska, I, Dommels, YEM, King, M, Elliot, R, Pico, C & Keijer, J 2006, 'Nutrient-gene interactions in benefit-risk analysis', British Journal of Nutrition, vol. 95, no. 6, pp. 1232-1236. https://doi.org/10.1079/BJN20061749

Nutrient-gene interactions in benefit-risk analysis. / Hesketh, J.; Wybranska, I.; Dommels, Y.E.M.; King, M.; Elliot, R.; Pico, C.; Keijer, J.

In: British Journal of Nutrition, Vol. 95, No. 6, 2006, p. 1232-1236.

Research output: Contribution to journalArticleAcademicpeer-review

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Hesketh J, Wybranska I, Dommels YEM, King M, Elliot R, Pico C et al. Nutrient-gene interactions in benefit-risk analysis. British Journal of Nutrition. 2006;95(6):1232-1236. https://doi.org/10.1079/BJN20061749