NSP1 of the GRAS protein family is essential for Rhizobial Nod factor-induced transcription

P. Smit, J.G.J. Raedts, V. Portyanko, F. Debellé, C. Gough, T. Bisseling, R. Geurts

Research output: Contribution to journalArticleAcademicpeer-review

364 Citations (Scopus)

Abstract

Rhizobial Nod factors induce in their legume hosts the expression of many genes and set in motion developmental processes leading to root nodule formation. Here we report the identification of the Medicago GRAS-type protein Nodulation signaling pathway 1 (NSP1), which is essential for all known Nod factor–induced changes in gene expression. NSP1 is constitutively expressed, and so it acts as a primary transcriptional regulator mediating all known Nod factor–induced transcriptional responses, and therefore, we named it a Nod factor response factor.
LanguageEnglish
Pages1789-1791
JournalScience
Volume308
Issue number5729
DOIs
Publication statusPublished - 2005

Fingerprint

Transcription Factors
Gene Expression
Medicago
Fabaceae
Proteins

Keywords

  • receptor kinase gene
  • medicago-truncatula
  • bacterial
  • fungal
  • identification
  • transduction
  • symbiosis
  • mutants
  • calcium

Cite this

Smit, P. ; Raedts, J.G.J. ; Portyanko, V. ; Debellé, F. ; Gough, C. ; Bisseling, T. ; Geurts, R. / NSP1 of the GRAS protein family is essential for Rhizobial Nod factor-induced transcription. In: Science. 2005 ; Vol. 308, No. 5729. pp. 1789-1791.
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NSP1 of the GRAS protein family is essential for Rhizobial Nod factor-induced transcription. / Smit, P.; Raedts, J.G.J.; Portyanko, V.; Debellé, F.; Gough, C.; Bisseling, T.; Geurts, R.

In: Science, Vol. 308, No. 5729, 2005, p. 1789-1791.

Research output: Contribution to journalArticleAcademicpeer-review

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AU - Smit, P.

AU - Raedts, J.G.J.

AU - Portyanko, V.

AU - Debellé, F.

AU - Gough, C.

AU - Bisseling, T.

AU - Geurts, R.

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KW - receptor kinase gene

KW - medicago-truncatula

KW - bacterial

KW - fungal

KW - identification

KW - transduction

KW - symbiosis

KW - mutants

KW - calcium

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