Novel Enzymatic Synthesis of 3-hydroxybutyric Acid Oligomerswith Inserted Lactobionic Acid Moieties

S. Kakasi-Zsurka, A. Todea, A. But, C. Paul, C.G. Boeriu, A. Nagv, C.M. Davidescu, F. Peter

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

3-Hydroxybutyric acid and lactobionic acid yielded linear and cyclic oligomers in a lipase-catalyzedcondensation polymerization reaction, performed at 80°C in bulk and organic solvent systems. Novozyme435 was the most efficient biocatalyst, and a mixture of t-butanol and dimethylsulfoxide in 80:20 (v/v) ratioprovided the highest copolymer conversions. The highest degree of polymerization reached 7 in case ofcopolymers with inserted lactobionic acid moiety and 11 for the 3-hydroxybutyric acid homopolymer by-product.
Original languageEnglish
Pages (from-to)958-963
JournalRevista de Chimie
Volume62
Issue number10
Publication statusPublished - 2011

Keywords

  • polymerization
  • lipase
  • polyesters

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    Kakasi-Zsurka, S., Todea, A., But, A., Paul, C., Boeriu, C. G., Nagv, A., ... Peter, F. (2011). Novel Enzymatic Synthesis of 3-hydroxybutyric Acid Oligomerswith Inserted Lactobionic Acid Moieties. Revista de Chimie, 62(10), 958-963.