Noval fungal expression system.

L.H. de Graaff (Inventor), H.C. van den Broeck (Inventor), J. Visser (Inventor), F. Buxton (Inventor)

Research output: Patent


The invention relates to the field of genetic engineering and provides novel DNA molecules comprising a fungal promoter. The novel DNA molecules are useful for the construction of hybrid vectors expressing genes in filamentous fungi. Objects of the invention are novel DNA molecules comprising the A. niger pki promoter, hybrid vectors useful for the expression of structural genes under the control of said promoter, hosts transformed with the novel hybrid vectors, and processes for the production of the novel DNA molecules, hybrid vectors, and transformed hosts and for the production of recombinant polypeptides by means of said transformed hosts
Original languageEnglish
Patent numberEP0439997
Priority date29/01/90
Publication statusPublished - 1990


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