No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study

R.C. Bröring, I.A. Brouwer, R. Vliegenthart, F.J.A. van Rooij, J.C. Witteman, J.M. Geleijnse

Research output: Contribution to journalMeeting AbstractAcademic

Abstract

Background: Fish and EPA/DHA intake is inversely related to risk of CHD. The underlying mechanism for this cardioprotective effect, however, is not yet clear. Objective: To examine fish and EPA/DHA intake in relation to calcification of the coronary arteries in a general Dutch population. Methods: Coronary calcification was detected with electron beam computed tomography between 1997-2000 in 1,570 subjects who were free of CHD (44% male, mean age: 64 y). Severe calcification was defined as an Agatston score >400. Dietary intake, including fish consumed during dinner, lunch and between meals, was assessed in 1990-1993 with a semiquantitative FFQ. Prevalence ratios (PR) for severe calcification were obtained by log-binomial regression (reference: Agatston score =20 vs. 0 g/d was 0.98 (95% CI: 0.75-1.27) in men and 0.85 (0.57-1.28) in women. PR for EPA/DHA (upper vs. lower tertile) were 0.94 (0.74-1.19) in men and 1.11 (0.76-1.62) in women. Conclusion: Our data do not support a role for EPA/DHA in coronary calcification in a general older population with a low or moderate level of fish intake
Original languageEnglish
Pages (from-to)E340-P264
JournalCirculation
Volume119
Issue number10
Publication statusPublished - 2009

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Omega-3 Fatty Acids
Fishes
Meals
Lunch
X Ray Computed Tomography
Population
Coronary Vessels

Cite this

Bröring, R. C., Brouwer, I. A., Vliegenthart, R., van Rooij, F. J. A., Witteman, J. C., & Geleijnse, J. M. (2009). No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study. Circulation, 119(10), E340-P264.
Bröring, R.C. ; Brouwer, I.A. ; Vliegenthart, R. ; van Rooij, F.J.A. ; Witteman, J.C. ; Geleijnse, J.M. / No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study. In: Circulation. 2009 ; Vol. 119, No. 10. pp. E340-P264.
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title = "No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study",
abstract = "Background: Fish and EPA/DHA intake is inversely related to risk of CHD. The underlying mechanism for this cardioprotective effect, however, is not yet clear. Objective: To examine fish and EPA/DHA intake in relation to calcification of the coronary arteries in a general Dutch population. Methods: Coronary calcification was detected with electron beam computed tomography between 1997-2000 in 1,570 subjects who were free of CHD (44{\%} male, mean age: 64 y). Severe calcification was defined as an Agatston score >400. Dietary intake, including fish consumed during dinner, lunch and between meals, was assessed in 1990-1993 with a semiquantitative FFQ. Prevalence ratios (PR) for severe calcification were obtained by log-binomial regression (reference: Agatston score =20 vs. 0 g/d was 0.98 (95{\%} CI: 0.75-1.27) in men and 0.85 (0.57-1.28) in women. PR for EPA/DHA (upper vs. lower tertile) were 0.94 (0.74-1.19) in men and 1.11 (0.76-1.62) in women. Conclusion: Our data do not support a role for EPA/DHA in coronary calcification in a general older population with a low or moderate level of fish intake",
author = "R.C. Br{\"o}ring and I.A. Brouwer and R. Vliegenthart and {van Rooij}, F.J.A. and J.C. Witteman and J.M. Geleijnse",
year = "2009",
language = "English",
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Bröring, RC, Brouwer, IA, Vliegenthart, R, van Rooij, FJA, Witteman, JC & Geleijnse, JM 2009, 'No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study' Circulation, vol. 119, no. 10, pp. E340-P264.

No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study. / Bröring, R.C.; Brouwer, I.A.; Vliegenthart, R.; van Rooij, F.J.A.; Witteman, J.C.; Geleijnse, J.M.

In: Circulation, Vol. 119, No. 10, 2009, p. E340-P264.

Research output: Contribution to journalMeeting AbstractAcademic

TY - JOUR

T1 - No Association of Fish and Omega-3 Fatty Acid Intake with Coronary Calcification: The Rotterdam Coronary Calcification Study

AU - Bröring, R.C.

AU - Brouwer, I.A.

AU - Vliegenthart, R.

AU - van Rooij, F.J.A.

AU - Witteman, J.C.

AU - Geleijnse, J.M.

PY - 2009

Y1 - 2009

N2 - Background: Fish and EPA/DHA intake is inversely related to risk of CHD. The underlying mechanism for this cardioprotective effect, however, is not yet clear. Objective: To examine fish and EPA/DHA intake in relation to calcification of the coronary arteries in a general Dutch population. Methods: Coronary calcification was detected with electron beam computed tomography between 1997-2000 in 1,570 subjects who were free of CHD (44% male, mean age: 64 y). Severe calcification was defined as an Agatston score >400. Dietary intake, including fish consumed during dinner, lunch and between meals, was assessed in 1990-1993 with a semiquantitative FFQ. Prevalence ratios (PR) for severe calcification were obtained by log-binomial regression (reference: Agatston score =20 vs. 0 g/d was 0.98 (95% CI: 0.75-1.27) in men and 0.85 (0.57-1.28) in women. PR for EPA/DHA (upper vs. lower tertile) were 0.94 (0.74-1.19) in men and 1.11 (0.76-1.62) in women. Conclusion: Our data do not support a role for EPA/DHA in coronary calcification in a general older population with a low or moderate level of fish intake

AB - Background: Fish and EPA/DHA intake is inversely related to risk of CHD. The underlying mechanism for this cardioprotective effect, however, is not yet clear. Objective: To examine fish and EPA/DHA intake in relation to calcification of the coronary arteries in a general Dutch population. Methods: Coronary calcification was detected with electron beam computed tomography between 1997-2000 in 1,570 subjects who were free of CHD (44% male, mean age: 64 y). Severe calcification was defined as an Agatston score >400. Dietary intake, including fish consumed during dinner, lunch and between meals, was assessed in 1990-1993 with a semiquantitative FFQ. Prevalence ratios (PR) for severe calcification were obtained by log-binomial regression (reference: Agatston score =20 vs. 0 g/d was 0.98 (95% CI: 0.75-1.27) in men and 0.85 (0.57-1.28) in women. PR for EPA/DHA (upper vs. lower tertile) were 0.94 (0.74-1.19) in men and 1.11 (0.76-1.62) in women. Conclusion: Our data do not support a role for EPA/DHA in coronary calcification in a general older population with a low or moderate level of fish intake

M3 - Meeting Abstract

VL - 119

SP - E340-P264

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 10

ER -