Next-Generation Sequencing in the Mycology Lab

Jan Zoll*, Eveline Snelders, Paul E. Verweij, Willem J.G. Melchers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)

Abstract

New state-of-the-art techniques in sequencing offer valuable tools in both detection of mycobiota and in understanding of the molecular mechanisms of resistance against antifungal compounds and virulence. Introduction of new sequencing platform with enhanced capacity and a reduction in costs for sequence analysis provides a potential powerful tool in mycological diagnosis and research. In this review, we summarize the applications of next-generation sequencing techniques in mycology.

Original languageEnglish
Pages (from-to)37-42
Number of pages6
JournalCurrent Fungal Infection Reports
Volume10
Issue number2
DOIs
Publication statusPublished - 16 Mar 2016
Externally publishedYes

Keywords

  • Clinical mycology lab issues
  • Mycobiome
  • Next-generation sequencing
  • Resistance
  • Review
  • Whole genome sequencing

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