Abstract
Newcastle disease (ND) is one of the most important infectious diseases of poultry. It is caused by virulent Avian avulavirus 1 (AAvV-1), also known as Newcastle disease virus (NDV) or Avian paramyxovirus 1 (APMV-1). Since the mid-1920s, ND has spread throughout the world. The use of vaccines derived from naturally occurring AAvV-1 strains has limited the economic losses due to ND. However, due to antigenic differences between vaccine and outbreak strains, vaccination does not prevent replication and spread of these viruses. Therefore, new genotype-matched vaccines are urgently needed.
Original language | English |
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Title of host publication | Encyclopedia of Virology |
Editors | Dennis H. Bamford, Mark Zuckerman |
Publisher | Elsevier |
Pages | 648-653 |
Number of pages | 6 |
Volume | 1-5 |
Edition | 4 |
ISBN (Electronic) | 9780128145166 |
DOIs | |
Publication status | Published - 2021 |
Keywords
- Avian Avulavirus
- Avian paramyxovirus
- Avulavirus
- Genotype
- Lentogenic
- Mesogenic
- Neurotropic
- Newcastle disease
- Paramyxovirus
- Pathotype
- Phylogeny
- Poultry disease
- Velogenic
- Viscerotropic