Neuro-endocrine regulation of LH secretion in cyclic pigs

J. Dierx

Research output: Thesisinternal PhD, WU


The present thesis describes the study in the hormonal (endocrine) regulation of the fertility in the female pig. Fertility is optimal when during the reproductive cycle the concentrations of hormones change in a particular sequence. In the present thesis it has been shown that, amongst others, morphine-like substances (endorphins) play a role in the timing of this sequence. The effects of these substances are predominantly at the level of the brain (central nervous system). The activity of the endorphins can be mediated by factors in the environment. Such factors, for example, are a change in housing condition and chronic stress. In this way, these environmental factors can lead to disturbances in the reproductive cycle.

Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Wiegant, V.M., Promotor
  • van der Heide, D., Promotor
Award date15 Jan 1999
Place of PublicationWageningen
Print ISBNs9789054859574
Publication statusPublished - 1999


  • sows
  • lh
  • oestrous cycle
  • stress


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